3-COUMARANONE

Synonym(s):3-Coumaranone

CAS NO.：7169-34-8
Empirical Formula: C8H6O2
Molecular Weight: 134.13
MDL number: MFCD00051810
EINECS: 640-279-1
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is 3-COUMARANONE?

Chemical properties

white to light yellow crystal powde

The Uses of 3-COUMARANONE

3-Coumaranone is used in the aurones, [2-benzylidenebenzofuran-3(2H)-ones] by reacting with appropriate aldehyde. It is involved in the condensation reaction with aldehydes in the presence of morpholine acetate to prepare substituted 2-(arylidene)benzofuran-3(ZH)-ones. In Horner-Wadsworth-Emmons reaction, it reacts with diethyl? cyanomethyl?phosphonate to give 3-(cyanomethyl)benzofurans, which is an intermediate in the synthesis of antihyperglycemic agents.

What are the applications of Application

Benzofuran-3(2H)-one is undergoes condensation with aldehydes in the presence of morpholine acetate to yield substituted 2-(arylidene)benzofuran-3(ZH)-ones

General Description

Benzofuran-3(2H)-one undergoes condensation with aldehydes in the presence of morpholine acetate to yield substituted 2-(arylidene)benzofuran-3(ZH)-ones. It undergoes acid- or base-catalyzed condensation with an appropriate aldehyde to yield aurones [2-benzylidenebenzofuran-3(2H)-ones].

Properties of 3-COUMARANONE

Melting point:	101-103 °C
Boiling point:	207.23°C (rough estimate)
Density	1.1603 (rough estimate)
refractive index	1.4800 (estimate)
storage temp.	Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility	Chloroform (Slightly), DMSO (Slightly)
form	Solid
color	Yellow to Dark Yellow
Water Solubility	Slightly miscible with water.
Sensitive	Light Sensitive
BRN	115296
CAS DataBase Reference	7169-34-8(CAS DataBase Reference)
NIST Chemistry Reference	3(2H)-benzofuranone(7169-34-8)

Safety information for 3-COUMARANONE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H332:Acute toxicity,inhalation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.