3-Bromoquinoline

CAS NO.：5332-24-1
Empirical Formula: C9H6BrN
Molecular Weight: 208.05
MDL number: MFCD00006767
EINECS: 226-237-1
SAFETY DATA SHEET (SDS)
Update Date: 2023-12-14 20:49:34

What is 3-Bromoquinoline?

Chemical properties

colorless to light yellow liquid

Synthesis Reference(s)

The Journal of Organic Chemistry, 27, p. 1318, 1962 DOI: 10.1021/jo01051a047

General Description

3-Bromoquinoline undergoes bromine-magnesium exchange reaction with lithium tributylmagnesate in toluene at -10°C, which is quenched by various electrophiles to yield functionalized quinolines.

Flammability and Explosibility

Not classified

Properties of 3-Bromoquinoline

Melting point:	13-15 °C (lit.)
Boiling point:	274-276 °C (lit.)
Density	1.533 g/mL at 25 °C (lit.)
vapor pressure	0.196Pa at 25℃
refractive index	n20/D 1.664(lit.)
Flash point:	>230 °F
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
pka	2.69(at 25℃)
form	Liquid
color	Clear colorless to yellow
Water Solubility	103mg/L at 25℃
BRN	112939
CAS DataBase Reference	5332-24-1(CAS DataBase Reference)
NIST Chemistry Reference	Quinoline, 3-bromo-(5332-24-1)
EPA Substance Registry System	Quinoline, 3-bromo- (5332-24-1)

Safety information for 3-Bromoquinoline

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.