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HomeProduct name list3-BROMOIMIDAZO[1,2-B]PYRIDAZINE

3-BROMOIMIDAZO[1,2-B]PYRIDAZINE

3-BROMOIMIDAZO[1,2-B]PYRIDAZINE Structural

What is 3-BROMOIMIDAZO[1,2-B]PYRIDAZINE?

The Uses of 3-BROMOIMIDAZO[1,2-B]PYRIDAZINE

3-Bromoimidazo[1,2-B]pyridazine is a pharmaceutical intermediate compound. It is used in the preparation of Ponatinib, a tyrosine kinase inhibitor (TKI), which is used in the treatment of chronic myeloid leukaemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukaemia (Ph+ ALL).

Properties of 3-BROMOIMIDAZO[1,2-B]PYRIDAZINE

Melting point: 148.0 to 152.0 °C
Density  1.89
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
form  powder to crystal
pka 2.35±0.30(Predicted)
color  White to Light yellow
CAS DataBase Reference 18087-73-5

Safety information for 3-BROMOIMIDAZO[1,2-B]PYRIDAZINE

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H332:Acute toxicity,inhalation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.
P310:Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 3-BROMOIMIDAZO[1,2-B]PYRIDAZINE

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