3-Bromo-9H-carbazole
- CAS NO.:1592-95-6
- Empirical Formula: C12H8BrN
- Molecular Weight: 246.1
- MDL number: MFCD00222621
- EINECS: 679-545-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-08 10:32:02
What is 3-Bromo-9H-carbazole?
Chemical properties
White to light yellow solid
The Uses of 3-Bromo-9H-carbazole
3-Bromo-9H-carbazole is an aryl hydrocarbon receptor agonist. A standard for environmental testing and research. Substance for the bological potency study, characterization of mono to tetra-halogenated carbazoles.
The Uses of 3-Bromo-9H-carbazole
3-Bromocarbazole is used as a intermediate for organic light-emitting diode(OLED) and pharmaceutical.
Preparation
3-Bromocarbazole synthesis: A solution of N-bromosuccinimide (1.1g, 5.98mmol) in dimethylformamide was added dropwise to a solution of carbazole (1, 1g, 5.96mmol) in dimethylformamide (15mL) at 0°C. The reaction mixture was then stirred at room temperature for 24h. The reaction was poured into distilled water to give a cream coloured precipitate. The precipitate was filtered off under vacuum and washed with distilled water (3 × 20mL). The precipitate was dissolved in ethyl acetate, dried with sodium sulfate and filtered. Upon concentration under reduced pressure the crude product was obtained as a brown solid. After crystallisation of the crude product with chloroform, the pure 3-Bromo-9H-carbazole(692 mg, 47%) was obtained as white crystals. Rf (ethyl acetate/hexane, 1:6 v/v): 0.43; melting point: 200–201°C.
Properties of 3-Bromo-9H-carbazole
Melting point: | 195 °C |
Boiling point: | 160℃/6mm |
Density | 1.617±0.06 g/cm3(Predicted) |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
form | Solid |
pka | 16.43±0.30(Predicted) |
color | White |
Water Solubility | Slightly soluble in water. |
EPA Substance Registry System | 3-Bromocarbazole (1592-95-6) |
Safety information for 3-Bromo-9H-carbazole
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 3-Bromo-9H-carbazole
InChIKey | LTBWKAYPXIIVPC-UHFFFAOYSA-N |
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