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HomeProduct name list3-Bromo-2-pyridinamine

3-Bromo-2-pyridinamine

  • CAS NO.:13534-99-1
  • Empirical Formula: C5H5BrN2
  • Molecular Weight: 173.01
  • MDL number: MFCD03095187
  • EINECS: 629-620-5
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-03-19 13:53:49
3-Bromo-2-pyridinamine Structural

What is 3-Bromo-2-pyridinamine?

Chemical properties

grey to brown powder

The Uses of 3-Bromo-2-pyridinamine

2-Amino-3-bromopyridine may be used to synthesize:

  • 2-acylamido-3-bromopyridines
  • 2-anilino-3-bromopyridine
  • 3-[(2-methoxyphenyl)ethynyl]pyridin-2-amine
  • 3-[(4-methoxyphenyl)ethynyl]pyridin-2-amine
  • N-(bromopyridyl)amidines
  • carbolines via palladium catalyzed arylation followed by palladium catalyzed amination reaction
  • 2-amino-3-cyanopyridine via palladium catalyzed cyanation reaction with potassium ferro-cyanide in the presence of 1,8-diazabicyclo[5.4.0]undec-7-ene [DBU]
  • nitro-substituted N,N′-dipyridinylamines via palladium catalyzed coupling reaction with 2-chloro-3-nitropyridine in the presence of Xantphos ligand
  • 2-amino-3-iodopyridine via reaction with sodium iodide in the presence of copper(I)iodide and trans-N,N′-dimethylcyclohexane-1,2-diamine

Properties of 3-Bromo-2-pyridinamine

Melting point: 63-67 °C
Boiling point: 232.0±20.0 °C(Predicted)
Density  1.6065 (rough estimate)
vapor pressure  0.83-1.8Pa at 20-25℃
refractive index  1.5182 (estimate)
storage temp.  Keep in dark place,Inert atmosphere,Room temperature
form  Powder
pka 4.14±0.36(Predicted)
color  Gray to brown
BRN  109867
CAS DataBase Reference 13534-99-1(CAS DataBase Reference)

Safety information for 3-Bromo-2-pyridinamine

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 3-Bromo-2-pyridinamine

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