(3-BENZYLOXYPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE
- CAS NO.：54314-85-1
- Empirical Formula: C28H28BrOP
- Molecular Weight: 491.4
- MDL number: MFCD00191781
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is (3-BENZYLOXYPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE?
The Uses of (3-BENZYLOXYPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE
(3-Benzyloxypropyl)triphenylphosphonium Bromide is a reagent used in the preparation of antitumor and Her2 degradation activity of geldanamycin and radicicol macrocyclic chimeras.
The Uses of (3-BENZYLOXYPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE
Reactant for preparation of:
- Spirocyclohexadienones via Pd-catalyzed intramolecular ipso-Friedel-Crafts allylic alkylation
- Inhibitors of heat shock protein (Hsp90) as antitumor agents
- Carpanone-like molecules via an oxidative coupling/Diels-Alder cycloaddition sequence
What are the applications of Application
(3-Benzyloxypropyl)triphenylphosphonium bromide is a useful wittig reagent to create antitumor compounds
Properties of (3-BENZYLOXYPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE
| Melting point: | 153-154 °C (lit.) |
| form | Powder |
| color | White to off-white |
Safety information for (3-BENZYLOXYPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for (3-BENZYLOXYPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE
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