3'-Azido-3'-deoxythymidine-5'-triphosphate
- CAS NO.：92586-35-1
- Empirical Formula: C10H16N5O13P3·xLi
- Molecular Weight: 0
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 16:48:35
What is 3'-Azido-3'-deoxythymidine-5'-triphosphate?
The Uses of 3'-Azido-3'-deoxythymidine-5'-triphosphate
3'-Azido-3'-deoxythymidine 5’-Triphosphate Tetraammonium Salt, is used for the preparation of drug against human retroviruses.
Biological Activity
AZT triphosphate (3'-Azido-3'-deoxythymidine-5'-triphosphate) is an active triphosphate metabolite of Zidovudine (AZT). It has antiretroviral activity and inhibits HIV replication.
in vitro
AZT triphosphate causes mitochondrial dysfunction, increases the production of cytotoxic reactive oxygen species (ROS), and impairs the balance of the mitochondrial quality control system in H9c2 cell model established from rat embryonic myoblasts.
Properties of 3'-Azido-3'-deoxythymidine-5'-triphosphate
| storage temp. | Store at -20°C |
| solubility | Methanol (Slightly), Water (Slightly) |
| form | Sticky Solid |
| color | Off-White |
| Stability: | Hygroscopic |
Safety information for 3'-Azido-3'-deoxythymidine-5'-triphosphate
Computed Descriptors for 3'-Azido-3'-deoxythymidine-5'-triphosphate
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![3'-AZIDO 3'-DEOXYTHYMIDINE 5'-TRIPHOSPHATE, TETRATRIETHYLAMMONIUM SALT, [METHYL-3H]-](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB0262277.gif)
![3'-AZIDO-3'-DEOXYTHYMIDINE-5'-TRIPHOSPHATE, [2-13C-1,3-15N]-](https://img.chemicalbook.in/StructureFile/ChemBookStructure9/GIF/CB0243410.gif)
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