Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name list3-((2,2,2- trifluoroethyl)thio)aniline

3-((2,2,2- trifluoroethyl)thio)aniline

  • CAS NO.:1445684-99-0
  • Empirical Formula: C8H8F3NS
  • Molecular Weight: 207.22
  • MDL number: MFCD21805732
  • EINECS: 000-000-0
  • Update Date: 2023-04-14 17:55:39
3-((2,2,2- trifluoroethyl)thio)aniline Structural

What is 3-((2,2,2- trifluoroethyl)thio)aniline?

The Uses of 3-((2,2,2- trifluoroethyl)thio)aniline

3-((2,2,2-trifluoroethyl)thio)aniline can be used as an intermediate in pharmaceutical research.

Synthesis

To a solution of 3-aminobenzenethiol (4.43 g, 35.4 mmol) in THF (225 mL) was added sodium hydride (1.77 g, 44.3 mmol) at 0 °C and stirred for 30 min. Then, 2,2,2-trifluoroethyl 4- methylbenzenesulfonate (9.0 g, 35.4 mmol) was added and the reaction mixture was stirred for 18 h. The reaction mixture was quenched with water (20 mL) and extracted with EtOAc (2x50 mL). The combined organic extracts were washed with water, dried over Na2SO4, fdtered, and concentrated under reduced pressure. The crude residue was purified by flash chromatography through a Redi-Sep pre-packed silica gel column, eluting with a gradient of 5 % to 10 % EtOAc in hexanes, to give 3-((2,2,2- trifluoroethyl)thio)aniline (5 g, 68 % yield) as a pale brown oil.

Safety information for 3-((2,2,2- trifluoroethyl)thio)aniline

Related products of tetrahydrofuran

You may like

  • 1-Methyl-6-oxo-1,6-dihydropyridazine-3-carbonitrile 98%
    1-Methyl-6-oxo-1,6-dihydropyridazine-3-carbonitrile 98%
    99903-60-3
    View Details
  • 88491-46-7 98%
    88491-46-7 98%
    88491-46-7
    View Details
  • 1823368-42-8 98%
    1823368-42-8 98%
    1823368-42-8
    View Details
  • 2-(3-(tert-butyl)phenoxy)-2-methylpropanoic acid 1307449-08-6 98%
    2-(3-(tert-butyl)phenoxy)-2-methylpropanoic acid 1307449-08-6 98%
    1307449-08-6
    View Details
  • Ethyl 3-(furan-2-yl)-3-hydroxypropanoate 25408-95-1 98%
    Ethyl 3-(furan-2-yl)-3-hydroxypropanoate 25408-95-1 98%
    25408-95-1
    View Details
  • 2-Chloro-5-fluoro-1-methoxy-3-methylbenzene 98%
    2-Chloro-5-fluoro-1-methoxy-3-methylbenzene 98%
    1805639-70-6
    View Details
  • 1784294-80-9 98%
    1784294-80-9 98%
    1784294-80-9
    View Details
  • Lithium Clavulanate
    Lithium Clavulanate
    61177-44-4
    View Details
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.