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HomeProduct name list2,6-Dimethoxypyridine-3-carboxylic acid

2,6-Dimethoxypyridine-3-carboxylic acid

Synonym(s):2,6-Dimethoxynicotinic acid

2,6-Dimethoxypyridine-3-carboxylic acid Structural

What is 2,6-Dimethoxypyridine-3-carboxylic acid?

The Uses of 2,6-Dimethoxypyridine-3-carboxylic acid

2,6-Dimethoxypyridine-3-carboxylic acid (2,6-dimethoxynicotinic acid, DMPH) may be used in the preparation of novel benzothiazolo naphthyridone carboxylic acid derivatives. It may be used in the preparation of following complexes, via reaction with different precursors [Ti(η5-C5H5)2Cl2], [Ti(η5-C5H4Me)2Cl2], [Ti(η5-C5H4SiMe3)(η5-C5H5)Cl2], [Ti(η5-C5Me5)Cl3], SnMe3Cl and GatBu3:

  • [Ti(η5-C5H5)2(DMP-κO)2]
  • [Ti(η5-C5H4Me)2(DMP-κO)2]
  • [Ti(η5-C5H4SiMe3)(η5-C5H5)(DMP-κO)2
  • [Ti(η5-C5Me5)(DMP-κ2O,O′)3]
  • [SnMe3(μ-DMP-κO:κO′)]
  • [GatBu2(μ-DMP-κOO′)]2

General Description

2,6-Dimethoxypyridine-3-carboxylic acid (2,6-Dimethoxynicotinic acid, DMNIH) is a piperidine derivative. It forms various organotin(IV) complexes and their antiproliferative action against pancreatic carcinoma (PANC-1), erythroleukemia (K562), and two glioblastoma multiform (U87 and LN-229) human cell lines has been evaluated.

Properties of 2,6-Dimethoxypyridine-3-carboxylic acid

Melting point: 140-144 °C (lit.)
Boiling point: 293.1±35.0 °C(Predicted)
Density  1.279±0.06 g/cm3(Predicted)
storage temp.  Inert atmosphere,Room Temperature
pka 3.63±0.10(Predicted)
form  Crystalline Powder
color  White to pale yellow

Safety information for 2,6-Dimethoxypyridine-3-carboxylic acid

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 2,6-Dimethoxypyridine-3-carboxylic acid

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