2,6-Dimethoxypyridine-3-carboxylic acid
Synonym(s):2,6-Dimethoxynicotinic acid
- CAS NO.：16727-43-8
- Empirical Formula: C8H9NO4
- Molecular Weight: 183.16
- MDL number: MFCD00075582
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is 2,6-Dimethoxypyridine-3-carboxylic acid?
The Uses of 2,6-Dimethoxypyridine-3-carboxylic acid
2,6-Dimethoxypyridine-3-carboxylic acid (2,6-dimethoxynicotinic acid, DMPH) may be used in the preparation of novel benzothiazolo naphthyridone carboxylic acid derivatives. It may be used in the preparation of following complexes, via reaction with different precursors [Ti(η5-C5H5)2Cl2], [Ti(η5-C5H4Me)2Cl2], [Ti(η5-C5H4SiMe3)(η5-C5H5)Cl2], [Ti(η5-C5Me5)Cl3], SnMe3Cl and GatBu3:
- [Ti(η5-C5H5)2(DMP-κO)2]
- [Ti(η5-C5H4Me)2(DMP-κO)2]
- [Ti(η5-C5H4SiMe3)(η5-C5H5)(DMP-κO)2
- [Ti(η5-C5Me5)(DMP-κ2O,O′)3]
- [SnMe3(μ-DMP-κO:κO′)]∞
- [GatBu2(μ-DMP-κO:κO′)]2
General Description
2,6-Dimethoxypyridine-3-carboxylic acid (2,6-Dimethoxynicotinic acid, DMNIH) is a piperidine derivative. It forms various organotin(IV) complexes and their antiproliferative action against pancreatic carcinoma (PANC-1), erythroleukemia (K562), and two glioblastoma multiform (U87 and LN-229) human cell lines has been evaluated.
Properties of 2,6-Dimethoxypyridine-3-carboxylic acid
| Melting point: | 140-144 °C (lit.) |
| Boiling point: | 293.1±35.0 °C(Predicted) |
| Density | 1.279±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| pka | 3.63±0.10(Predicted) |
| form | Crystalline Powder |
| color | White to pale yellow |
Safety information for 2,6-Dimethoxypyridine-3-carboxylic acid
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2,6-Dimethoxypyridine-3-carboxylic acid
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