2',6'-Dihydroxyacetophenone

Synonym(s):2-Acetyl-1,3-dihydroxybenzene;2-Acetylresorcinol;DHAP

CAS NO.：699-83-2
Empirical Formula: C8H8O3
Molecular Weight: 152.15
MDL number: MFCD00002270
EINECS: 211-833-6
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-01 18:09:03

What is 2',6'-Dihydroxyacetophenone?

Chemical properties

yellowish-beige powder

The Uses of 2',6'-Dihydroxyacetophenone

2'',6''-Dihydroxyacetophenone (cas# 699-83-2) is a compound useful in organic synthesis.

The Uses of 2',6'-Dihydroxyacetophenone

Used with diammonium hydrogen citrate for MALDI-MS of PMP-labeled acidic and neutral glycans.

Preparation

Preparation by hydrolysis of 8-acetyl-4-methyl-umbelliferone (8-acetyl-7-hydroxy-4-methylcoumarin) with aqueous sodium hydroxide solution at reflux (56–73%).

Definition

ChEBI: 2',6'-Dihydroxyacetophenone is an aromatic ketone.

Properties of 2',6'-Dihydroxyacetophenone

Melting point:	156-158 °C(lit.)
Boiling point:	234.6°C (rough estimate)
Density	1.2143 (rough estimate)
refractive index	1.4447 (estimate)
storage temp.	Inert atmosphere,Room Temperature
solubility	dioxane: 50 mg/mL, clear
pka	9.65±0.10(Predicted)
form	Powder
color	Yellow-beige
Water Solubility	sparingly soluble
BRN	1366061
CAS DataBase Reference	699-83-2(CAS DataBase Reference)
NIST Chemistry Reference	2',6'-Dihydroxyacetophenone(699-83-2)

Safety information for 2',6'-Dihydroxyacetophenone

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.