2,5-DIMETHOXYPROPIOPHENONE
- CAS NO.：5803-30-5
- Empirical Formula: C11H14O3
- Molecular Weight: 194.23
- MDL number: MFCD00027013
- EINECS: 227-357-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-08 17:06:38
What is 2,5-DIMETHOXYPROPIOPHENONE?
The Uses of 2,5-DIMETHOXYPROPIOPHENONE
2'',5''-Dimethoxypropiophenone is a component of essential oils of some plants in the Asarum genus. It is also a useful building block and has been used in the preparation of methoxamine hydrochloride.
Preparation
Obtained by acylation of hydroquinone dimethyl ether,
with propionyl chloride in the presence of aluminium chloride in petroleum ether (34%), in carbon disulfide, or using 10% mol. samarium triiodide in acetonitrile (60%)
with propionic anhydride in the presence of aluminium chloride in nitromethane
with propionic acid in the presence of PPA at 70° for 2 h (95%)
in the presence of zeolite catalyst.
Properties of 2,5-DIMETHOXYPROPIOPHENONE
| Melting point: | 8°C |
| Boiling point: | 168°C/13mmHg(lit.) |
| Density | 1.047±0.06 g/cm3(Predicted) |
| refractive index | 1.5340 to 1.5380 |
| form | clear liquid |
| color | Light orange to Yellow to Green |
| CAS DataBase Reference | 5803-30-5(CAS DataBase Reference) |
Safety information for 2,5-DIMETHOXYPROPIOPHENONE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2,5-DIMETHOXYPROPIOPHENONE
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