2,5-Di-tert-butyl-1,4-benzoquinone

CAS NO.：2460-77-7
Empirical Formula: C14H20O2
Molecular Weight: 220.31
MDL number: MFCD00019442
EINECS: 219-552-0
SAFETY DATA SHEET (SDS)
Update Date: 2023-05-04 17:34:36

What is 2,5-Di-tert-butyl-1,4-benzoquinone?

Chemical properties

Yellow to golden crystalline powder

Definition

ChEBI: 2,5-di-tert-Butyl-1,4-benzoquinone is a member of p-quinones and a member of benzoquinones.

Synthesis Reference(s)

The Journal of Organic Chemistry, 46, p. 4545, 1981 DOI: 10.1021/jo00335a045
Synthetic Communications, 10, p. 615, 1980 DOI: 10.1080/00397918008063598
Tetrahedron Letters, 35, p. 5083, 1994 DOI: 10.1016/S0040-4039(00)73327-2

General Description

2,5-Di-tert-butyl-1,4-benzoquinone (DTBBQ) is an 2,5-disubstituted quinone. It is an antibacterial compound. It has been isolated from marine Streptomyces sp. VITVSK1. Pressure dependance on the intramolecular and intermolecular migration rates of Na⁺ and K⁺ in a 2,5-di-tert-butyl-1,4-benzoquinone ion pair have been evaluated by using a high-pressure EPR technique.

Flammability and Explosibility

Flammable

Properties of 2,5-Di-tert-butyl-1,4-benzoquinone

Melting point:	152-154 °C (lit.)
Boiling point:	321.25°C (rough estimate)
Density	1.0106 (rough estimate)
vapor pressure	0.241Pa at 20℃
refractive index	1.4970 (estimate)
storage temp.	Sealed in dry,Room Temperature
form	powder to crystal
color	White to Yellow to Orange
Water Solubility	18.716mg/L at 25℃
BRN	2047945
CAS DataBase Reference	2460-77-7(CAS DataBase Reference)
EPA Substance Registry System	2,5-Cyclohexadiene-1,4-dione, 2,5-bis(1,1-dimethylethyl)- (2460-77-7)

Safety information for 2,5-Di-tert-butyl-1,4-benzoquinone

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.