2,5-BIS(4-AMINOPHENYL)-1,3,4-OXADIAZOLE

Synonym(s):BAO

CAS NO.：2425-95-8
Empirical Formula: C14H12N4O
Molecular Weight: 252.27
MDL number: MFCD00042667
EINECS: 219-373-8
SAFETY DATA SHEET (SDS)
Update Date: 2023-06-08 17:06:38

2,5-BIS(4-AMINOPHENYL)-1,3,4-OXADIAZOLE Structural

What is 2,5-BIS(4-AMINOPHENYL)-1,3,4-OXADIAZOLE?

The Uses of 2,5-BIS(4-AMINOPHENYL)-1,3,4-OXADIAZOLE

Aromatic polyimides were synthesized from 2, 5-bis(4-aminophenyl)-1,3,4-oxadiazole and 2,5-diamino-pyridine via high temperature polycondensation. BAO may be used to undertake Schiff-type staining of DNA obtained from cerebral cortex neurons. It may be used for cytofluorometric staining to estimate the nuclear DNA in living and preserved algae.

General Description

2, 5-Bis-(4-aminophenyl)-1, 3, 4-oxadiazole (BAO) is an oxadiazole-containing rigid bidentate ligands.

Purification Methods

BAO is recrystallised from EtOH using charcoal and under N2 to avoid oxidation. It is a fluorescent stain for DNA [Yataghanas et al. Exptl Cell Res 56 59 1969]. [Beilstein 27 III/IV 8158.]

Properties of 2,5-BIS(4-AMINOPHENYL)-1,3,4-OXADIAZOLE

Melting point:	250-254 °C(lit.)
Boiling point:	508.1±60.0 °C(Predicted)
Density	1.301±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
form	powder to crystal
pka	2.53±0.10(Predicted)
color	Light orange to Yellow to Green
BRN	243757
CAS DataBase Reference	2425-95-8(CAS DataBase Reference)

Safety information for 2,5-BIS(4-AMINOPHENYL)-1,3,4-OXADIAZOLE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.