2,4,6-Trimethylphenylacetonitrile

Synonym(s):Mesitylacetonitrile

CAS NO.：34688-71-6
Empirical Formula: C11H13N
Molecular Weight: 159.23
MDL number: MFCD00013815
EINECS: 252-151-9
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

2,4,6-Trimethylphenylacetonitrile Structural

What is 2,4,6-Trimethylphenylacetonitrile?

Chemical properties

white to off-white crystals or crystalline powder

The Uses of 2,4,6-Trimethylphenylacetonitrile

2,4,6-Trimethylphenylacetonitrile (Mesitylacetonitrile) may be used in the preparation of 2,4,6-trimethyl-,9-phenethylamine hydrochloride. It may also be employed in the synthesis of the following compounds:

ethyl mesitylacetate
α-mesitylacetoacetonitrile
mesitylacetone
β-hydroxy-a-mesitylacrylonitrile
α-mesitylpropionic acid
α-mesityl-8-phenylpropionitrile

The Uses of 2,4,6-Trimethylphenylacetonitrile

2-Mesitylacetonitrile, is an organic building block used in the synthesis of more complex compounds, such as Spiromesifen Metabolite (M225645). It can also be used in the novel synthetic route for the Anti-HIV Drug MC-1220 and its analogues.

General Description

2,4,6-Trimethylphenylacetonitrile is formed as an intermediate during the synthesis of mesitylacetic acid.

Properties of 2,4,6-Trimethylphenylacetonitrile

Melting point:	76-80 °C(lit.)
Boiling point:	120 °C (1 mmHg)
Density	1.0293 (rough estimate)
refractive index	1.5466 (estimate)
Flash point:	120°C/1mm
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Solid
color	White to Off-White
BRN	1942677
Exposure limits	NIOSH: IDLH 25 mg/m3
CAS DataBase Reference	34688-71-6(CAS DataBase Reference)
NIST Chemistry Reference	2,4,6-Trimethylbenzyl cyanide(34688-71-6)

Safety information for 2,4,6-Trimethylphenylacetonitrile

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.