2,4,6-Tribromoaniline
- CAS NO.:147-82-0
- Empirical Formula: C6H4Br3N
- Molecular Weight: 329.81
- MDL number: MFCD00007634
- EINECS: 205-700-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-09-19 18:11:18
What is 2,4,6-Tribromoaniline?
Chemical properties
BEIGE TO GREY CRYSTALLINE SOLID
The Uses of 2,4,6-Tribromoaniline
2,4,6-Tribromoaniline was used in simultaneous determination of phenolic brominated flame retardants and their by-products in water.
The Uses of 2,4,6-Tribromoaniline
A trihalogen substituted aniline with potential inhibitory effect on human cytochrome P 450 (CYP) 2E1.
Preparation
2,4,6-Tribromoaniline can be prepared by treating bromine water with aniline in a solution of acetic acid or dilute hydrochloric acid:
synthesis-of-2-4-6-tribromoaniline-from-aniline
General Description
Electrochemical oxidation of 2,4,6-tribromoaniline in aqueous sulphuric acid solutions at platinum electrode has been studied by rotating disc electrode and cyclic voltammetry. 2,4,6-Tribromoaniline on closed-tube pyrolysis yields polybromophenazines. It is an intermediate in the formulation of flame retardants incorporated to plastic materials.
Purification Methods
Crystallise the aniline from MeOH. The benzenesulfonamide derivative has m 198o. [Beilstein 12 H 663, 12 I 329, 12 II 358, 12 III 1477, 12 IV 1538.]
Properties of 2,4,6-Tribromoaniline
Melting point: | 120-122 °C(lit.) |
Boiling point: | 300 °C(lit.) |
Density | 2.35 |
refractive index | 1.6890 (estimate) |
Flash point: | 300°C |
solubility | alcohol: soluble (cold)(lit.) |
form | powder to crystal |
pka | -0.23±0.10(Predicted) |
color | White to Almost white |
Merck | 14,9610 |
BRN | 2209258 |
CAS DataBase Reference | 147-82-0(CAS DataBase Reference) |
NIST Chemistry Reference | Benzenamine, 2,4,6-tribromo-(147-82-0) |
EPA Substance Registry System | 2,4,6-Tribromoaniline (147-82-0) |
Safety information for 2,4,6-Tribromoaniline
Signal word | Danger |
Pictogram(s) |
Corrosion Corrosives GHS05 Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08 |
GHS Hazard Statements |
H301:Acute toxicity,oral H311:Acute toxicity,dermal H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation H319:Serious eye damage/eye irritation H332:Acute toxicity,inhalation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H373:Specific target organ toxicity, repeated exposure |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P311:Call a POISON CENTER or doctor/physician. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 2,4,6-Tribromoaniline
InChIKey | GVPODVKBTHCGFU-UHFFFAOYSA-N |
Abamectin manufacturer
Faluck International
ALS INDIA LIFE SCIENCES
Ralington Pharma
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