2,4-Dimethoxybenzylamine
- CAS NO.：20781-20-8
- Empirical Formula: C9H13NO2
- Molecular Weight: 167.21
- MDL number: MFCD00052811
- EINECS: 672-586-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-06 22:41:32
What is 2,4-Dimethoxybenzylamine?
Chemical properties
Colorless to light yellow liqui
The Uses of 2,4-Dimethoxybenzylamine
2,4-Dimethoxybenzylamine is an amine nucleophile used to investigate the 1,4- reactivity of 5-bromo-2-indene-1-one. It may be used in the following studies:
- As an ammonia equivalent in the concise synthesis of a series of 2,4,5-trisubstituted oxazoles, via a tandem Ugi/Robinson-Gabriel reaction sequence.
- Total synthesis of (-)-muraymycin (MRY) D2 and its epimer, the antibacterial nucleoside natural product.
- Two-step synthesis of amide derivatives of uracil polyoxin C (UPOC) methyl ester using the Ugi reaction.
- Synthesis of N-hydroxythiourea.
- Synthesis of anti-HIV-1 agents.
Preparation
2,4-Dimethoxybenzylamine can be preprepared by reduction (NaBH4 , BF3.OEt2, THF) of 2,4-dimethoxybenzonitrile.
Properties of 2,4-Dimethoxybenzylamine
| Boiling point: | 95 °C0.2 mm Hg(lit.) |
| Density | 1.113 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | >230 °F |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| pka | 9.39±0.10(Predicted) |
| form | Liquid |
| color | Clear colorless to slightly yellow |
| Sensitive | Air Sensitive |
| CAS DataBase Reference | 20781-20-8(CAS DataBase Reference) |
Safety information for 2,4-Dimethoxybenzylamine
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 2,4-Dimethoxybenzylamine
| InChIKey | QOWBXWFYRXSBAS-UHFFFAOYSA-N |
2,4-Dimethoxybenzylamine manufacturer
JSK Chemicals
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Sintilla Medcoms Pvt Ltd
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product: 2,4-Dimethoxybenzylamine 98%
Syn Finechem Laboratories Pvt Ltd.
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Phone:+91-9848230784
Whatsapp: +91 9848230784
product: 2,4-Dimethoxybenzylamine 98%
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