2,4-DIMETHOXY-4'-HYDROXYBENZOPHENONE
Synonym(s):(2,4-Dimethoxyphenyl)-(4-hydroxyphenyl)methanone;2,4-Dimethoxy-4′-hydroxybenzophenone
- CAS NO.：41351-30-8
- Empirical Formula: C15H14O4
- Molecular Weight: 258.27
- MDL number: MFCD00137850
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-08 17:06:38
What is 2,4-DIMETHOXY-4'-HYDROXYBENZOPHENONE?
Chemical properties
2,4-DIMETHOXY-4'-HYDROXYBENZOPHENONE is white to off-white powder
The Uses of 2,4-DIMETHOXY-4'-HYDROXYBENZOPHENONE
2,4-DIMETHOXY-4'-HYDROXYBENZOPHENONE is used for solid-phase peptide synthesis with FMOC strategy
What are the applications of Application
4′-Hydroxy-2,4-dimethoxybenzophenone is a linker employed for solid-phase peptide synthesis
Preparation
Preparation by Friedel–Crafts acylation of resorcinol dimethyl ether with p-hydroxybenzoic acid,
? in the presence of zinc chloride and phosphorous oxychloride at 60–65° for 1.5 h (71%) or in nitrobenzene at 60° for 2–3 h;
? in the presence of polyphosphoric acid.
Properties of 2,4-DIMETHOXY-4'-HYDROXYBENZOPHENONE
| Melting point: | 138-142 °C (lit.) |
| Boiling point: | 467.9±45.0 °C(Predicted) |
| Density | 1.206±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | soluble in Methanol |
| form | Powder |
| pka | 7.73±0.15(Predicted) |
| color | Off-white to white |
| BRN | 2508320 |
| CAS DataBase Reference | 41351-30-8(CAS DataBase Reference) |
Safety information for 2,4-DIMETHOXY-4'-HYDROXYBENZOPHENONE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2,4-DIMETHOXY-4'-HYDROXYBENZOPHENONE
2,4-DIMETHOXY-4'-HYDROXYBENZOPHENONE manufacturer
A.J Chemicals
New Delhi
Phone:91-9810153283
Whatsapp: 91-9810153283
product: 2,4-dimethoxy-4'-hydroxybenzophenone
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