2',3',4'-TRIHYDROXYACETOPHENONE

Synonym(s):2′,3′,4′-Trihydroxyacetophenone

YELLOW TO YELLOW-GREEN CRYSTALLINE POWDER

Antiseptic.

2,3,4-Trihydroxyacetophenone is used as a reagent in the synthesis of chromenone and quinolinone derivatives as potent antioxidant agents.

Preparation by Fries rearrangement of pyrogallol triacetate with aluminium chloride without solvent.

ChEBI: 2',3',4'-Trihydroxyacetophenone is an aromatic ketone.

Melting point:	169-172 °C(lit.)
Boiling point:	257.07°C (rough estimate)
Density	1.3037 (rough estimate)
refractive index	1.5090 (estimate)
pka	7.81±0.23(Predicted)
form	powder to crystal
color	White to Orange to Green
Merck	14,4342
CAS DataBase Reference	528-21-2(CAS DataBase Reference)
NIST Chemistry Reference	Ethanone, 1-(2,3,4-trihydroxyphenyl)-(528-21-2)
EPA Substance Registry System	Ethanone, 1-(2,3,4-trihydroxyphenyl)- (528-21-2)

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.