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HomeProduct name list2',3'-O-Isopropylideneguanosine

2',3'-O-Isopropylideneguanosine

  • CAS NO.:362-76-5
  • Empirical Formula: C13H17N5O5
  • Molecular Weight: 323.3
  • MDL number: MFCD00057081
  • EINECS: 206-651-9
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-05-18 11:31:20
2',3'-O-Isopropylideneguanosine Structural

What is 2',3'-O-Isopropylideneguanosine?

Chemical properties

White Crystalline Solid

The Uses of 2',3'-O-Isopropylideneguanosine

2',3'-O-Isopropylideneguanosine is a useful precursor for the preparation of nucleic acids

The Uses of 2',3'-O-Isopropylideneguanosine

A useful precursor for the preparation of nucleic acids.

Synthesis

Add 10 mL of anhydrous pyridine to 2 g (7.45 mmol) of solid 2',3'-O-Isopropylideneguanosine to form a white suspension.
1 Remove the pyridine under reduced pressure to remove any trapped water;
2 Repeat the previous step;
3 Add 5 mL of acetone to the residue and stir for 30 minutes;
4 Add 50 mL of ether to the mixture and stir for 1 hour;
5 Filter the resulting precipitate and wash it with ether;
6 Dry the product in a vacuum desiccator over P2O5.

Properties of 2',3'-O-Isopropylideneguanosine

Melting point: 296 °C
Density  1.93±0.1 g/cm3(Predicted)
storage temp.  Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility  DMSO, 15% Ammonium Hydroxide, Hot 50% aq. Ethanol, Methanol, Warm Water
form  Solid
pka 9?+-.0.20(Predicted)
color  White to Off-White
InChI InChI=1S/C13H17N5O5/c1-13(2)22-7-5(3-19)21-11(8(7)23-13)18-4-15-6-9(18)16-12(14)17-10(6)20/h4-5,7-8,11,19H,3H2,1-2H3,(H3,14,16,17,20)/t5-,7-,8-,11-/m1/s1
CAS DataBase Reference 362-76-5(CAS DataBase Reference)

Safety information for 2',3'-O-Isopropylideneguanosine

Computed Descriptors for 2',3'-O-Isopropylideneguanosine

InChIKey XKPDAYWPKILAMO-IOSLPCCCSA-N
SMILES OC[C@H]1O[C@@H](N2C3=C(C(NC(=N3)N)=O)N=C2)[C@@H]2OC(O[C@H]12)(C)C

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