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HomeProduct name list2',3'-DIDEOXY-3'-FLUOROURIDINE

2',3'-DIDEOXY-3'-FLUOROURIDINE

Synonym(s):3′-Fluoro-2′,3′-dideoxyuridine

  • CAS NO.:41107-56-6
  • Empirical Formula: C9H11FN2O4
  • Molecular Weight: 230.19
  • MDL number: MFCD00192015
  • EINECS: 415-360-8
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-10-28 23:16:16
2',3'-DIDEOXY-3'-FLUOROURIDINE Structural

What is 2',3'-DIDEOXY-3'-FLUOROURIDINE?

Chemical properties

Off-white solid

The Uses of 2',3'-DIDEOXY-3'-FLUOROURIDINE

2'',3''-Dideoxy-3''-fluorouridine is a reactant used in the synthesis of 5''-trityl nucleosides as inhibitors of Plasmodium falciparum dUTPase.

The Uses of 2',3'-DIDEOXY-3'-FLUOROURIDINE

2′,3′-Dideoxy-3′-fluorouridine can be used as a starting material in the synthesis of:

  • 3′-fluoro 2′,3′-dideoxynucleoside analogs for in vitro antiviral activity studies.
  • 3′-fluoro deoxyuridine monophosphate analogs as potential anti parasites.

What are the applications of Application

2′,3′-Dideoxy-3′-fluorouridine is an anti-retroviral compound

General Description

2′,3′-Dideoxy-3′-fluorouridine (3′-fluoro-2′,3′-dideoxyuridine, FddUrd) is a fluorinated pyrimidine nucleoside analog of uridine. It has been studied extensively for its potential use as an antiviral agent against HIV.

Properties of 2',3'-DIDEOXY-3'-FLUOROURIDINE

Melting point: 184-188 °C(lit.)
Density  1.50±0.1 g/cm3(Predicted)
storage temp.  -20°C Freezer
solubility  Aqueous Base (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly), Water
pka 9.39±0.10(Predicted)
form  Solid
color  White to Off-White
optical activity [α]20/D +10.5°, c = 0.5 in 1 M NaOH
BRN  6064366

Safety information for 2',3'-DIDEOXY-3'-FLUOROURIDINE

Signal word Warning
Pictogram(s)
ghs
Health Hazard
GHS08
GHS Hazard Statements H341:Germ cell mutagenicity
Precautionary Statement Codes P281:Use personal protective equipment as required.

Computed Descriptors for 2',3'-DIDEOXY-3'-FLUOROURIDINE

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