2,2,6,6-Tetramethyl-4-piperidone hydrochloride
- CAS NO.:33973-59-0
- Empirical Formula: C9H18ClNO
- Molecular Weight: 191.7
- MDL number: MFCD00012768
- EINECS: 251-769-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-04-17 18:22:24

What is 2,2,6,6-Tetramethyl-4-piperidone hydrochloride?
Chemical properties
white to slightly beige crystalline powder
The Uses of 2,2,6,6-Tetramethyl-4-piperidone hydrochloride
2,2,6,6-Tetramethyl-4-piperidone hydrochloride has been used as a reagent injected in the micromixer using a Rheodyne injection valve for introducing discrete sample pulses into the miniaturised-SYNthesis and Total Analysis System (πSYNTAS).
Purification Methods
Purify the salt by recrystallisation from EtOH/Et2O, MeCN or Me2CO/MeOH. The free base has m 37-39o (after sublimation), b 102-105o/18mm, and the hydrate has m 56-58o (wet Et2O); the hydrobromide has m 203o (from EtOH/Et2O), and the picrate has m 196o (from aqueous EtOH). [Sandris & Ourisson Bull Soc Chim Fr 345 1958, Beilstein 21 H 246, 21 I 273, 21 II 222, 21 III/IV 3278, 21/6 V 538.]
Properties of 2,2,6,6-Tetramethyl-4-piperidone hydrochloride
Melting point: | 198 °C (dec.)(lit.) |
storage temp. | Sealed in dry,Room Temperature |
color | White to off-white |
BRN | 4154554 |
CAS DataBase Reference | 33973-59-0(CAS DataBase Reference) |
EPA Substance Registry System | 4-Piperidinone, 2,2,6,6-tetramethyl-, hydrochloride (33973-59-0) |
Safety information for 2,2,6,6-Tetramethyl-4-piperidone hydrochloride
Signal word | Warning |
Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2,2,6,6-Tetramethyl-4-piperidone hydrochloride
New Products
4-Piperidinemethanol Ethyl 2,4-Dihydroxy-6-methylnicotinate Ethyl isonicotinate 3-pyridine methanol N-Methyl 4-chloro-pyridine-2-carboxamide 2-Fluoro-6-iodobenzoic acid 2-((2,6-difluorobenzyl)(ethoxycarbonyl)amino)-4-((dimethylamino)methyl)-5-(4-nitrophenyl)thiophene-3-carboxylic acid Ethyl2-oxo-2,3,9,10-tetrahydro-1H-pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxaline-8(7H)-carboxylate Elinzanetant tert-butyl 2-(4-amino-6-chloropyrimidin-5-yloxy)ethylmethylcarbamate Phenylazomalononitrile 5,6 Dimethoxy-1-indanone 3-Iodophenylacetic acid 2-Hexyn-1-ol Dibenzo-18-crown-6 2-Propanamine, 1-chloro-, hydrochloride (9CI) 3-Pyridineacetonitrile, α-hydroxy- 3-(hexyloxy)-4-(pyridin-3-yl)-1,2,5-thiadiazole N Ethylmethylamine Ethyl Methanesulfonate N N' DimethylEthylenediamine Lead II Bromide Variamine Blue B Diazonium salt N N N'Trimethyl ethylenediamineRelated products of tetrahydrofuran








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