2,2'-Thiodiethanol
Synonym(s):2,2′-Thiobis(ethanol);Bis(2-hydroxyethyl) sulfide;Thiodiethylene glycol;Thiodiglycol
- CAS NO.:111-48-8
- Empirical Formula: C4H10O2S
- Molecular Weight: 122.19
- MDL number: MFCD00002910
- EINECS: 203-874-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-02-27 17:16:38

What is 2,2'-Thiodiethanol?
Chemical properties
colourless liquid with characteristic odour.
The Uses of 2,2'-Thiodiethanol
antineoplastic, alkylating agent
Definition
ChEBI: A diol that is pentane-1,5-diol in which the methylene group at position 3 is replaced by a sulfur atom
Hazard
Do not use with hydrochloric acid.
Flammability and Explosibility
Not classified
Properties of 2,2'-Thiodiethanol
Melting point: | −16 °C(lit.) |
Boiling point: | 164-166 °C20 mm Hg(lit.) |
Density | 1.221 g/mL at 25 °C(lit.) |
vapor pressure | 0.26Pa at 20℃ |
refractive index | n |
Flash point: | >230 °F |
storage temp. | -20°C |
solubility | alcohol: miscible(lit.) |
form | liquid |
pka | 14.14±0.10(Predicted) |
Merck | 14,9330 |
BRN | 1236325 |
Stability: | Stable. Incompatible with strong oxidizing agents. Reacts with a wide variety of compounds. Flammable. |
CAS DataBase Reference | 111-48-8(CAS DataBase Reference) |
NIST Chemistry Reference | Thiodiglycol(111-48-8) |
EPA Substance Registry System | Ethanol, 2,2'-thiobis- (111-48-8) |
Safety information for 2,2'-Thiodiethanol
Signal word | Warning |
Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H319:Serious eye damage/eye irritation |
Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for 2,2'-Thiodiethanol
New Products
3-Iodophenylacetic acid 3-Pyridineacetonitrile, α-hydroxy- 2-Propanamine, 1-chloro-, hydrochloride (9CI) 3-(hexyloxy)-4-(pyridin-3-yl)-1,2,5-thiadiazole 2-Hexyn-1-ol Dibenzo-18-crown-6 Nickel(II) perchlorate hexahydrate, 98% 4-Bromophenylacetonitrile, 95% 3-Bromo-4-fluoroaniline, 97% Sodium tetraborate decahydrate, 98% Palladium(II) acetate, trimer, Pd 99% 4-Bromo-2-chlorotoluene, 97% N N Dimethylformamide Dimethyl Acetal (Dmf Dma) 2,3-Dichloro Benzoyl Cyanide [Side Chain] Bis(2-Chloroethyl) Amine Hydrochloride L-Glutamic Acid Diethyl Ester Hydrochloride 5-(Difluoromethoxy)-2-Mercaptobenzimidazole 1-Ethyl-3-(3-Dimethylaminopropyl)-Carbodiimide Hydrochloride [EDC Hcl] 1,4-Napthoquinone Bromoiodomethane Sodium Bicarbonate Methylene Dichloride (MDC) Ethyl Acetate Indole-3-Carbinol (I3C)Related products of tetrahydrofuran
![Bis[2-(succiniMidooxycarbonyloxy)ethyl] Sulfone](https://img.chemicalbook.in/CAS/GIF/57683-72-4.gif)






![2-[(2-PHENOXYETHYL)THIO]ACETIC ACID](https://img.chemicalbook.in/CAS/GIF/75434-70-7.gif)
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