2-Piperidineethanol
Synonym(s):2-(2-Hydroxyethyl)piperidine
- CAS NO.：1484-84-0
- Empirical Formula: C7H15NO
- Molecular Weight: 129.2
- MDL number: MFCD00005989
- EINECS: 216-059-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-08 17:06:37
What is 2-Piperidineethanol?
Chemical properties
Off-White Solid
The Uses of 2-Piperidineethanol
2-Piperidineethanol is useful in preparation of a novel class of pyrazolopyrimidines as inhibitors of protein and checkpoint kinases useful in treatment and prophylaxis of HCV infection and other diseases such as cancer.
The Uses of 2-Piperidineethanol
Heterocyclic compound used in cosmetic compositions.
The Uses of 2-Piperidineethanol
Reactant for syntehsis of:
Spiroimidazolidinone NPC1L1 inhibitors
P2Y12 antagonists for inhibition of platelet aggregation
Cyclin-dependent kinase inhibitors
Anti-HIV agents
Tetraponerine analogs
Reactant for cyclization of secondary homoallylic amines
Synthesis
2-Piperidineethanol is produced from 2-alpha-Pyridylethanol by hydrogenation.
Properties of 2-Piperidineethanol
| Melting point: | 38-40 °C (lit.) |
| Boiling point: | 234 °C (lit.) |
| Density | 1.01 |
| vapor pressure | 0.75-13.04Pa at 20-50℃ |
| refractive index | 1.4749 (estimate) |
| Flash point: | >230 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Chloroform, Methanol |
| pka | 15.15±0.10(Predicted) |
| form | Crystalline Low Melting Solid |
| color | White to pale yellow |
| Odor | Mild, sweet, nauseating-floral, warm-herbaceous odor of moderate tenacity. |
| Water Solubility | soluble |
| CAS DataBase Reference | 1484-84-0(CAS DataBase Reference) |
| NIST Chemistry Reference | 2-(2-Hydroxyethyl)piperidine(1484-84-0) |
| EPA Substance Registry System | 2-Piperidineethanol (1484-84-0) |
Safety information for 2-Piperidineethanol
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-Piperidineethanol
| InChIKey | PTHDBHDZSMGHKF-UHFFFAOYSA-N |
2-Piperidineethanol manufacturer
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