2-PIPERIDIN-4-YL-1H-BENZOIMIDAZOLE
- CAS NO.:38385-95-4
- Empirical Formula: C12H15N3
- Molecular Weight: 201.27
- MDL number: MFCD01475843
- EINECS: 609-547-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-08-17 21:30:02
What is 2-PIPERIDIN-4-YL-1H-BENZOIMIDAZOLE?
The Uses of 2-PIPERIDIN-4-YL-1H-BENZOIMIDAZOLE
2-Piperidin-4-yl-1H-benzimidazole is used as a reagent in the synthesis of 3-amino-1-(5-indanyloxy)-2-propanol derivatives as potent sodium channel blockers for the treatment of ischemic stroke. Also used as a reagent in the synthesis of 2,3,5-trisubstituted pyridine derivatives as potent Akt1/Akt2 dual inhibitors.
Properties of 2-PIPERIDIN-4-YL-1H-BENZOIMIDAZOLE
Melting point: | 230 °C (decomp)(Solv: water (7732-18-5)) |
Boiling point: | 441.3±38.0 °C(Predicted) |
Density | 1.167±0.06 g/cm3(Predicted) |
vapor pressure | 0Pa at 25℃ |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
solubility | soluble in Methanol |
pka | 11.83±0.10(Predicted) |
form | Solid |
color | White to Light yellow to Light orange |
λmax | 279nm(MeOH)(lit.) |
Safety information for 2-PIPERIDIN-4-YL-1H-BENZOIMIDAZOLE
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-PIPERIDIN-4-YL-1H-BENZOIMIDAZOLE
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6-BROMO-2-PIPERIDIN-4-YL-1H-BENZOIMIDAZOLE
1-METHYL-2-PIPERIDIN-4-YL-1H-BENZIMIDAZOLE
N-(3-METHOXYPHENYL)-4-(5-METHYL-1H-BENZIMIDAZOL-2-YL)PIPERIDINE-1-CARBOXAMIDE
2-(1-[3-(TRIFLUOROMETHYL)BENZYL]PIPERIDIN-4-YL)-1H-BENZIMIDAZOLE
2-PIPERIDIN-4-YL-1H-BENZOIMIDAZOLE
2-(PIPERIDIN-4-YL)-1H-BENZO[D]IMIDAZOLE HYDROCHLORIDE
4-(5-METHYL-1H-BENZIMIDAZOL-2-YL)-N-[3-(TRIFLUOROMETHYL)PHENYL]PIPERIDINE-1-CARBOXAMIDE
5-FLUORO-2-PIPERIDIN-4-YL-1H-BENZOIMIDAZOLE,5-Fuoro-2-piperidin-4-yl-1H-benzoimidazole
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