2-PHENYLBUTYRAMIDE
Synonym(s):α-Ethylbenzeneacetamide;2-Phenylbutyramide
- CAS NO.:90-26-6
- Empirical Formula: C10H13NO
- Molecular Weight: 163.22
- MDL number: MFCD00025511
- EINECS: 201-980-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-04 17:34:43
What is 2-PHENYLBUTYRAMIDE?
Chemical properties
white crystalline powder or needles
The Uses of 2-PHENYLBUTYRAMIDE
α-Phenyl-α-ethylacetamide acts as a hypolipaemic agent used in the treatment of high levels of cholesterol.
The Uses of 2-PHENYLBUTYRAMIDE
antihypercholesterolemia
Definition
ChEBI: 2-phenylbutanamide is a member of acetamides.
Hazard
Moderately toxic by ingestion.
Safety Profile
A poison by intravenous route.Moderately toxic by ingestion. When heated todecomposition it emits toxic vapors of NOx.
Purification Methods
Crystallise the amide from H2O, EtOH, Et2O/pet ether or *C6H6. [Beilstein 9 I 212, 9 II 356, 9 III 2466.]
Properties of 2-PHENYLBUTYRAMIDE
Melting point: | 83-87 °C |
Boiling point: | 290.31°C (rough estimate) |
Density | 1.0508 (rough estimate) |
refractive index | 1.5718 (estimate) |
storage temp. | Refrigerator |
solubility | Chloroform (Slightly), Methanol (Slightly) |
pka | 16.28±0.50(Predicted) |
form | Crystalline Powder or Needles |
color | White |
CAS DataBase Reference | 90-26-6(CAS DataBase Reference) |
Safety information for 2-PHENYLBUTYRAMIDE
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 2-PHENYLBUTYRAMIDE
New Products
4-Fluorophenylacetic acid 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL Tert-butyl bis(2-chloroethyl)carbamate 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid S-2-CHLORO PROPIONIC ACID ETHYL ISOCYANOACETATE 2-Bromo-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate (6-METHYL-[1,3]DITHIOLO[4,5-b]QUINOXALIN-2-ONE INDAZOLE-3-CARBOXYLIC ACID 4-IODO BENZOIC ACID (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5,6-Dimethoxyindanone 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 2-aminopropyl benzoate hydrochloride 1-(4-(aminomethyl)benzyl)urea hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
ALPHA-METHYL-ALPHA-PHENYLSUCCINIMIDE
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DIHYDRO-5-PHENYL-5-PROPYL-4,6(1H,5H)-PYRIMIDINEDIONE
(S)-MEPHENYTOIN
4-HYDROXYPHENOBARBITAL
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