Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name list2-Nitrofluorene

2-Nitrofluorene

  • CAS NO.:607-57-8
  • Empirical Formula: C13H9NO2
  • Molecular Weight: 211.22
  • MDL number: MFCD00001117
  • EINECS: 210-138-5
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-04-23 13:52:06
2-Nitrofluorene Structural

What is 2-Nitrofluorene?

Chemical properties

cream powder

The Uses of 2-Nitrofluorene

2-Nitrofluorene is a genotoxic compound and also a biomaker that affects the DNA of living organisms. An environmental pollutant.

What are the applications of Application

2-Nitrofluorene is a nitrated polycyclic aromatic hydrocarbon

Definition

ChEBI: A nitroarene that is fluorene substituted by a nitro group at position 2.

General Description

Cream-colored solid.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

Aromatic nitro compounds, such as 2-Nitrofluorene, range from slight to strong oxidizing agents. If mixed with reducing agents, including hydrides, sulfides and nitrides, they may begin a vigorous reaction that culminates in a detonation. The aromatic nitro compounds may explode in the presence of a base such as sodium hydroxide or potassium hydroxide even in the presence of water or organic solvents. The explosive tendencies of aromatic nitro compounds are increased by the presence of multiple nitro groups. Stable under normal conditions. Protect from bases.

Health Hazard

ACUTE/CHRONIC HAZARDS: Toxic. Hazardous decomposition products. Carcinogen.

Safety Profile

Confirmed carcinogen with experimental carcinogenic and tumorigenic data. Moderately toxic by intraperitoneal route. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also NITRO COMPOUNDS OF AROMATIC HYDROCARBONS.

Metabolic pathway

Lung microsomal metabolism of 2-nitrofluorene (NF) increases in parallel with the accumulation of P-450b homologous mRNA and microsomal cytochrome P- 450b protein concentration. The formation of the major metabolite, and potent mutagen, 9-hydroxy-2- nitrofluorene (9-OHNF) is significantly inhibited by the addition of polyclonal anti-P-450b-IgG, and by the addition of the inhibitor, proadifen, to incubations with lung microsomal protein.

Purification Methods

Crystallise 2-nitrofluorene from aqueous acetic acid or Me2CO (m 158-158.5o, also 160-160.5o). [Beilstein 5 H 628, 5 III 1948.]

Properties of 2-Nitrofluorene

Melting point: 156-158 °C (lit.)
Boiling point: 350.9°C (rough estimate)
Density  1.1868 (rough estimate)
refractive index  1.6060 (estimate)
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
form  Powder
color  White to brown
Water Solubility  Insoluble
Stability: Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference 607-57-8(CAS DataBase Reference)
IARC 2B (Vol. 46, 105) 2014
NIST Chemistry Reference Fluorene, 2-nitro-(607-57-8)
EPA Substance Registry System 2-Nitrofluorene (607-57-8)

Safety information for 2-Nitrofluorene

Signal word Warning
Pictogram(s)
ghs
Health Hazard
GHS08
ghs
Environment
GHS09
GHS Hazard Statements H351:Carcinogenicity
H411:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes P201:Obtain special instructions before use.
P273:Avoid release to the environment.
P308+P313:IF exposed or concerned: Get medical advice/attention.

Computed Descriptors for 2-Nitrofluorene

Related products of tetrahydrofuran

You may like

Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.