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HomeProduct name list2-Nitroethanol

2-Nitroethanol

  • CAS NO.:625-48-9
  • Empirical Formula: C2H5NO3
  • Molecular Weight: 91.07
  • MDL number: MFCD00007405
  • EINECS: 210-895-1
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-04-23 13:52:06
2-Nitroethanol Structural

What is 2-Nitroethanol?

Chemical properties

Clear yellow liquid

The Uses of 2-Nitroethanol

2-Nitroethanol is an aliphatic β-nitro alcohol used as an in vivo therapeutic corneoscleral crosslinking agents with higher order nitroalcohol. It also functions as a crosslinking reagent for scieral tissue cross-linking of the eye cornea for treating keratoconus and post-surgical keratectasia.

General Description

Mobile dark brown-red liquid with a pungent odor.

Air & Water Reactions

Hygroscopic. Insoluble in water.

Reactivity Profile

2-Nitroethanol is incompatible with strong oxidizing agents, strong bases, acid chlorides and acid anhydrides. 2-Nitroethanol has exploded under vacuum distillation(attributed to the presence of peroxides or alkali).

Fire Hazard

2-Nitroethanol is probably combustible.

Properties of 2-Nitroethanol

Melting point: -80 °C (lit.)
Boiling point: 194 °C/765 mmHg (lit.)
Density  1.27 g/mL at 25 °C (lit.)
refractive index  n20/D 1.445(lit.)
Flash point: >230 °F
storage temp.  under inert gas (nitrogen or Argon) at 2-8°C
solubility  Chloroform, DMSO, Methanol (Sparingly)
form  Liquid
pka 8.42±0.29(Predicted)
color  Clear yellow
BRN  1633753
CAS DataBase Reference 625-48-9(CAS DataBase Reference)
NIST Chemistry Reference Ethanol, 2-nitro-(625-48-9)
EPA Substance Registry System 2-Nitroethanol (625-48-9)

Safety information for 2-Nitroethanol

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 2-Nitroethanol

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