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HomeProduct name list2-Nitrobenzenesulfonyl chloride

2-Nitrobenzenesulfonyl chloride

  • CAS NO.:1694-92-4
  • Empirical Formula: C6H4ClNO4S
  • Molecular Weight: 221.62
  • MDL number: MFCD00007430
  • EINECS: 216-907-1
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-10-21 09:30:51
2-Nitrobenzenesulfonyl chloride Structural

What is 2-Nitrobenzenesulfonyl chloride?

Chemical properties

Off-white tot yellow crystalline powder

The Uses of 2-Nitrobenzenesulfonyl chloride

2-Nitrobenzenesulfonyl chloride acts as a reagent to form 2-nitrobenzenesulfonyl derivatives of alcohols and amines. It is also involved in the selective cleavage with thiophenol without displacement of the nitro group. Further, it is used in the preparation of renin inhibitors. In addition to this, it finds application as an anticonvulsant.

Production Methods

2-Nitrobenzenesulfonyl chloride is isolated as an intermediate in the production of 2-nitrobenzenesulfonic acid. When 2,2' - dinitrodiphenyl disulfide is chlorinated in an organic solvent the product is 2-nitrophenylsulfenyl chloride.

Properties of 2-Nitrobenzenesulfonyl chloride

Melting point: 63-67 °C(lit.)
Boiling point: 350.6±25.0 °C(Predicted)
Density  1.606±0.06 g/cm3(Predicted)
storage temp.  Store below +30°C.
form  powder to crystal
color  White to Yellow to Orange
Water Solubility  Soluble in toluene, tetrahydrofuran, methylene chloride, ethyl acetate and dimethylformamide. Insoluble in water.
Sensitive  Moisture Sensitive
BRN  521155
CAS DataBase Reference 1694-92-4(CAS DataBase Reference)
EPA Substance Registry System Benzenesulfonyl chloride, 2-nitro- (1694-92-4)

Safety information for 2-Nitrobenzenesulfonyl chloride

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
GHS Hazard Statements H314:Skin corrosion/irritation
Precautionary Statement Codes P260:Do not breathe dust/fume/gas/mist/vapours/spray.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P363:Wash contaminated clothing before reuse.
P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 2-Nitrobenzenesulfonyl chloride

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