2-NAPHTHYL PHOSPHATE MONOSODIUM SALT

Synonym(s):β-Naphthyl phosphate monosodium salt;2-Naphthyl phosphate monosodium salt;mono-Sodium 2-naphthyl phosphate sodium salt

CAS NO.：14463-68-4
Empirical Formula: C10H8NaO4P
Molecular Weight: 246.13
MDL number: MFCD00065914
EINECS: 238-452-8
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-29 11:48:30

2-NAPHTHYL PHOSPHATE MONOSODIUM SALT Structural

What is 2-NAPHTHYL PHOSPHATE MONOSODIUM SALT?

The Uses of 2-NAPHTHYL PHOSPHATE MONOSODIUM SALT

2-Naphthyl Phosphate, Monosodium Salt can be used as reagent/reactant in preparation mono, di and tri-?mannopyranosyl phosphates as mannose-?1-?phosphate prodrugs for potential CDG-?Ia therapy.

Purification Methods

Recrystallise it from H2O (10mL) containing NaCl (0.4g). The salt is collected by centrifugation and dried in a vacuum desiccator, m 203-205o (partially resolidifies and re-melts at 244o). It crystallises from MeOH (m 222-223o). The free acid is recrystallised several times by addition of 2.5 parts of hot CHCl3 to a hot solution of the free acid (1 part) in Me2CO (1.3 parts), m 177-178o. [Friedman & Seligmann J Am Chem Soc 73 5292 1951, Chanley & Feaggeson J Am Chem Soc 77 4002 1955, Beilstein 6 H 647, 6 III 2989, 6 IV 428.] See also entry on p 688 in Chapter 6.

Properties of 2-NAPHTHYL PHOSPHATE MONOSODIUM SALT

storage temp.	-20°C
BRN	3779148
CAS DataBase Reference	14463-68-4(CAS DataBase Reference)

Safety information for 2-NAPHTHYL PHOSPHATE MONOSODIUM SALT

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.