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HomeProduct name list2-METHYL-6-NITROBENZOIC ANHYDRIDE

2-METHYL-6-NITROBENZOIC ANHYDRIDE

Synonym(s):MNBA

2-METHYL-6-NITROBENZOIC ANHYDRIDE Structural

What is 2-METHYL-6-NITROBENZOIC ANHYDRIDE?

The Uses of 2-METHYL-6-NITROBENZOIC ANHYDRIDE

2-Methyl-6-nitrobenzoic anhydride can be used:

  • As a versatile lactonization reagent applicable in the preparation of varieties of macrolide natural products and lactones.
  • As a reaction promoter in the synthesis of carboxamide derivatives by using corresponding amines and carboxylic acids.
  • In the total synthesis of GRP78 inhibitor prunustatin A, antifungal compound (3R,16E,20E,23R)-(?)-eushearilide and an antiobestic drug tetrahydrolipstatin.

General Description

2-Methyl-6-nitrobenzoic anhydride is a reagent employed as a coupling promoter in the synthesis of amides, lactones, esters, and peptides.

Properties of 2-METHYL-6-NITROBENZOIC ANHYDRIDE

Melting point: 173-177 °C
Boiling point: 559.4±50.0 °C(Predicted)
Density  1.416±0.06 g/cm3(Predicted)
storage temp.  Inert atmosphere,Room Temperature
solubility  very faint turbidity in hot Toluene
form  powder to crystal
color  White to Yellow to Orange

Safety information for 2-METHYL-6-NITROBENZOIC ANHYDRIDE

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 2-METHYL-6-NITROBENZOIC ANHYDRIDE

InChIKey YEKPNMQQSPHKBP-UHFFFAOYSA-N

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