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HomeProduct name list2-Methyl-4-nitroindole

2-Methyl-4-nitroindole

2-Methyl-4-nitroindole Structural

What is 2-Methyl-4-nitroindole?

The Uses of 2-Methyl-4-nitroindole

2-Methyl-4-nitroindole is a useful synthetic intermediate in the synthesis of AZD1981, a CRTH2 receptor antagonist used in patients with moderate to severe COPD. 2-Methyl-4-nitroindole is also used as a reagent in the preparation of anti-angiogenic pyrroloazaflavones.

Synthesis Reference(s)

Tetrahedron Letters, 40, p. 5395, 1999 DOI: 10.1016/S0040-4039(99)01014-X

Properties of 2-Methyl-4-nitroindole

Melting point: 192-194 °C
Boiling point: 365.6±22.0 °C(Predicted)
Density  1.355±0.06 g/cm3(Predicted)
storage temp.  Sealed in dry,Room Temperature
pka 15.34±0.30(Predicted)

Safety information for 2-Methyl-4-nitroindole

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.

Computed Descriptors for 2-Methyl-4-nitroindole

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