Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name list2-METHOXYBENZENETHIOL

2-METHOXYBENZENETHIOL

Synonym(s):2-Mercaptoanisole;2-Methoxybenzenethiol;Thioguaiacol

  • CAS NO.:7217-59-6
  • Empirical Formula: C7H8OS
  • Molecular Weight: 140.2
  • MDL number: MFCD00004834
  • EINECS: 230-605-7
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-12-18 14:08:52
2-METHOXYBENZENETHIOL Structural

What is 2-METHOXYBENZENETHIOL?

Chemical properties

clear yellow liquid

Chemical properties

Colorless to yellowish liquid; pungent, onion aroma.

Occurrence

Reported found in coffee.

The Uses of 2-METHOXYBENZENETHIOL

2-Methoxythiophenol is used in the synthesis of berberine-thiophenyl hybrids as multifunctional agents. Inhibition of acetylcholinesterase, butyrylcholinesterase and AB aggregation antioxidant activity.

The Uses of 2-METHOXYBENZENETHIOL

2-Methoxythiophenol was used in the synthesis of:

  • (4S)-N-[(2S)-2-methy-3-(2-methoxyphenylthio)propanoyl]-4-phenyloxazolidin-2-one
  • 2-(4-fluorophenyl)-6-(2-methoxyphenylsulfanyl)imidazo[1,2-a]pyridine
  • 2-(2-methoxyphenylsulfanyl)benzoic acid

Definition

ChEBI: 2-Methoxybenzenethiol is a thiol.

Aroma threshold values

Meaty type, very high strength odor, recommend smelling in a 0.10% solution or less.

Taste threshold values

Meaty sausage taste at 1 ppm in water.

General Description

2-Methoxythiophenol is a sulfur-containing compound that can be used as a flavoring agent.

Synthesis

2-Methoxybenzenethiol is prepared:
1) from or(ho-Aminophenol-methylether via Diazoreaction.
2) from Sodium phenoxide plus Sulfur at 200° C. to yield 2: 2'-Dihydroxy-diphenyldisulfide. Reduction and Methylation afford the title ether.

Properties of 2-METHOXYBENZENETHIOL

Melting point: 306.7-313.7 °C (decomp)
Boiling point: 99 °C/8 mmHg (lit.)
Density  1.152 g/mL at 25 °C (lit.)
refractive index  n20/D 1.591(lit.)
FEMA  4159 | 2-MERCAPTOANISOLE
Flash point: 204 °F
storage temp.  under inert gas (nitrogen or Argon) at 2-8°C
solubility  H2O: insoluble
pka 6.62±0.43(Predicted)
form  Liquid
Specific Gravity 1.152
color  Clear yellow
Odor at 1.00 % in propylene glycol. meaty smoked sausage powdery sweet spicy phenolic sulfurous
Sensitive  Stench
JECFA Number 1666
BRN  2042178
Stability: Moisture Sensitive
CAS DataBase Reference 7217-59-6(CAS DataBase Reference)
EPA Substance Registry System Benzenethiol, 2-methoxy- (7217-59-6)

Safety information for 2-METHOXYBENZENETHIOL

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P270:Do not eat, drink or smoke when using this product.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 2-METHOXYBENZENETHIOL

Related products of tetrahydrofuran

You may like

Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.