2-METHOXYBENZENETHIOL

Chemical properties

clear yellow liquid

Chemical properties

Colorless to yellowish liquid; pungent, onion aroma.

Occurrence

Reported found in coffee.

The Uses of 2-METHOXYBENZENETHIOL

2-Methoxythiophenol is used in the synthesis of berberine-thiophenyl hybrids as multifunctional agents. Inhibition of acetylcholinesterase, butyrylcholinesterase and AB aggregation antioxidant activity.

The Uses of 2-METHOXYBENZENETHIOL

2-Methoxythiophenol was used in the synthesis of:

• (4S)-N-[(2S)-2-methy-3-(2-methoxyphenylthio)propanoyl]-4-phenyloxazolidin-2-one
• 2-(4-fluorophenyl)-6-(2-methoxyphenylsulfanyl)imidazo[1,2-a]pyridine
• 2-(2-methoxyphenylsulfanyl)benzoic acid

Definition

ChEBI: 2-Methoxybenzenethiol is a thiol.

Aroma threshold values

Meaty type, very high strength odor, recommend smelling in a 0.10% solution or less.

Taste threshold values

Meaty sausage taste at 1 ppm in water.

General Description

2-Methoxythiophenol is a sulfur-containing compound that can be used as a flavoring agent.

Synthesis

2-Methoxybenzenethiol is prepared：
1) from or(ho-Aminophenol-methylether via Diazoreaction.
2) from Sodium phenoxide plus Sulfur at 200° C. to yield 2: 2'-Dihydroxy-diphenyldisulfide. Reduction and Methylation afford the title ether.