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HomeProduct name list2-Hydroxy-4-methoxybenzaldehyde

2-Hydroxy-4-methoxybenzaldehyde

Synonym(s):2-Hydroxy-4-methoxybenzaldehyde;4-Methoxysalicylaldehyde;4-Methoxysalicylaldehyde, 2-Hydroxyanisaldehyde

  • CAS NO.:673-22-3
  • Empirical Formula: C8H8O3
  • Molecular Weight: 152.15
  • MDL number: MFCD00003327
  • EINECS: 211-604-0
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-12 15:22:20
2-Hydroxy-4-methoxybenzaldehyde Structural

What is 2-Hydroxy-4-methoxybenzaldehyde?

Chemical properties

creamy white to beige or light brown cryst. powder

The Uses of 2-Hydroxy-4-methoxybenzaldehyde

2-Hydroxy-4-methoxybenzaldehyde was used in the synthesis of Schiff base ligand.

Definition

ChEBI: 2-Hydroxy-4-methoxybenzaldehyde is a member of methoxybenzenes and a member of phenols.

Synthesis Reference(s)

Tetrahedron Letters, 7, p. 4153, 1966 DOI: 10.1016/0005-2760(66)90119-6

General Description

2-Hydroxy-4-methoxybenzaldehyde is the main component of root bark essential oil of Periploca sepium Bunge. It is a potential tyrosinase inhibitor present in African medicinal plants.

Properties of 2-Hydroxy-4-methoxybenzaldehyde

Melting point: 41-43 °C (lit.)
Boiling point: 124 °C / 12mmHg
Density  1.2143 (rough estimate)
refractive index  1.4447 (estimate)
FEMA  4435 | 2-HYDROXY-4-METHOXYBENZALDEHYDE
Flash point: >230 °F
storage temp.  Store below +30°C.
solubility  DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml
pka 7.79±0.10(Predicted)
form  Crystalline Powder
color  Creamy white to beige or light brown
Odor at 100.00 %. vanillin like
Water Solubility  Solubility in methanol is almost transparent. Insoluble in water.
Sensitive  Air Sensitive
BRN  1072443
CAS DataBase Reference 673-22-3(CAS DataBase Reference)
NIST Chemistry Reference Benzaldehyde, 2-hydroxy-4-methoxy-(673-22-3)
EPA Substance Registry System Benzaldehyde, 2-hydroxy-4-methoxy- (673-22-3)

Safety information for 2-Hydroxy-4-methoxybenzaldehyde

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405:Store locked up.

Computed Descriptors for 2-Hydroxy-4-methoxybenzaldehyde

InChIKey WZUODJNEIXSNEU-UHFFFAOYSA-N

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