2-Hydroxy-4-methoxybenzaldehyde
Synonym(s):2-Hydroxy-4-methoxybenzaldehyde;4-Methoxysalicylaldehyde;4-Methoxysalicylaldehyde, 2-Hydroxyanisaldehyde
- CAS NO.：673-22-3
- Empirical Formula: C8H8O3
- Molecular Weight: 152.15
- MDL number: MFCD00003327
- EINECS: 211-604-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-31 13:32:20
What is 2-Hydroxy-4-methoxybenzaldehyde?
Chemical properties
creamy white to beige or light brown cryst. powder
The Uses of 2-Hydroxy-4-methoxybenzaldehyde
2-Hydroxy-4-methoxybenzaldehyde was used in the synthesis of Schiff base ligand.
Definition
ChEBI: 2-Hydroxy-4-methoxybenzaldehyde is a member of methoxybenzenes and a member of phenols.
Synthesis Reference(s)
Tetrahedron Letters, 7, p. 4153, 1966 DOI: 10.1016/0005-2760(66)90119-6
General Description
2-Hydroxy-4-methoxybenzaldehyde is the main component of root bark essential oil of Periploca sepium Bunge. It is a potential tyrosinase inhibitor present in African medicinal plants.
Properties of 2-Hydroxy-4-methoxybenzaldehyde
| Melting point: | 41-43 °C (lit.) |
| Boiling point: | 124 °C / 12mmHg |
| Density | 1.2143 (rough estimate) |
| refractive index | 1.4447 (estimate) |
| FEMA | 4435 | 2-HYDROXY-4-METHOXYBENZALDEHYDE |
| Flash point: | >230 °F |
| storage temp. | Store below +30°C. |
| solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml |
| pka | 7.79±0.10(Predicted) |
| form | Crystalline Powder |
| color | Creamy white to beige or light brown |
| Odor | at 100.00 %. vanillin like |
| Water Solubility | Solubility in methanol is almost transparent. Insoluble in water. |
| Sensitive | Air Sensitive |
| BRN | 1072443 |
| CAS DataBase Reference | 673-22-3(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzaldehyde, 2-hydroxy-4-methoxy-(673-22-3) |
| EPA Substance Registry System | Benzaldehyde, 2-hydroxy-4-methoxy- (673-22-3) |
Safety information for 2-Hydroxy-4-methoxybenzaldehyde
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 2-Hydroxy-4-methoxybenzaldehyde
| InChIKey | WZUODJNEIXSNEU-UHFFFAOYSA-N |
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