2-Fluoropyridine
- CAS NO.：372-48-5
- Empirical Formula: C5H4FN
- Molecular Weight: 97.09
- MDL number: MFCD00006224
- EINECS: 206-757-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-05 19:05:58
What is 2-Fluoropyridine?
Chemical properties
CLEAR COLOURLESS TO LIGHT YELLOW LIQUID
The Uses of 2-Fluoropyridine
2-Fluoropyridine is a useful precursor of 2,3-disubstituted pyridines which is made by the possibility of metallation at C-3, together with the ready nucleophilic displacement of the activated fluorine. It can also react with thiophene to get 2-thiophen-2-yl-pyridine. It is used in the synthesis of aminopyridines.
Properties of 2-Fluoropyridine
| Boiling point: | 126 °C/753 mmHg (lit.) |
| Density | 1.128 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | 83 °F |
| storage temp. | Inert atmosphere,2-8°C |
| form | Liquid |
| pka | -0.44(at 25℃) |
| Specific Gravity | 1.13 |
| color | Clear colorless to light yellow |
| Water Solubility | Soluble in water. |
| BRN | 1515 |
| Dielectric constant | 37.289999999999999 |
| InChI | InChI=1S/C5H4FN/c6-5-3-1-2-4-7-5/h1-4H |
| CAS DataBase Reference | 372-48-5(CAS DataBase Reference) |
| NIST Chemistry Reference | 2-Fluoropyridine(372-48-5) |
Safety information for 2-Fluoropyridine
| Signal word | Warning |
| Pictogram(s) |
 Flame Flammables GHS02  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H226:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-Fluoropyridine
| InChIKey | MTAODLNXWYIKSO-UHFFFAOYSA-N |
| SMILES | C1(F)=NC=CC=C1 |
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