2-Fluoro-6-methylpyridine
Synonym(s):6-Fluoro-2-picoline
- CAS NO.：407-22-7
- Empirical Formula: C6H6FN
- Molecular Weight: 111.12
- MDL number: MFCD00041226
- EINECS: 206-980-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-30 18:52:02
What is 2-Fluoro-6-methylpyridine?
Chemical properties
liquid
The Uses of 2-Fluoro-6-methylpyridine
2-Fluoro-6-methylpyridine may be used in the preparation of:
- 2-fluoro-6-pyridinecarboxylic acid
- 2,2′-[1-(6-methylpyridin-2-yl)ethane-1,1-diyl]dipyridine
- 2-fluoropyridine-6-aldoxime
- 2-fluoro-6-(dibromomethyl)pyridine
Synthesis Reference(s)
Tetrahedron, 52, p. 23, 1996 DOI: 10.1016/0040-4020(95)00867-8
General Description
2-Fluoro-6-methylpyridine, also known as 2-fluoro-6-picoline, can be prepared via diazotization of 2-amino-6-methylpyridine in hydrogen fluoride containing 40% pyridine solution. The effect of substituents on spectral properties of 2-fluoro-6-methylpyridine has been investigated based on 13C NMR, UV and IR spectral data.
Properties of 2-Fluoro-6-methylpyridine
| Boiling point: | 140-141 °C (lit.) |
| Density | 1.077 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | 152 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | clear liquid |
| pka | 0.29±0.10(Predicted) |
| Specific Gravity | 1.07 |
| color | Colorless to Light orange to Yellow |
| BRN | 107084 |
| CAS DataBase Reference | 407-22-7(CAS DataBase Reference) |
| NIST Chemistry Reference | 2-Fluoro-6-methylpyridine(407-22-7) |
Safety information for 2-Fluoro-6-methylpyridine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-Fluoro-6-methylpyridine
| InChIKey | UDMNVTJFUISBFD-UHFFFAOYSA-N |
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