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HomeProduct name list2-Fluoro-5-bromobenzotrifluoride

2-Fluoro-5-bromobenzotrifluoride

2-Fluoro-5-bromobenzotrifluoride Structural

What is 2-Fluoro-5-bromobenzotrifluoride?

Chemical properties

Colorless liquid

The Uses of 2-Fluoro-5-bromobenzotrifluoride

Pharmaceutical Intermediates.

The Uses of 2-Fluoro-5-bromobenzotrifluoride

5-Bromo-2-fluorobenzotrifluoride may be used in the preparation of:

  • 3,5-bis(4-fluoro-3-trifluoromethylphenyl)phenol
  • 9,9-bis(2-ethylhexyl)-2,7-bis[4-fluoro-3-trifluoromethylphenyl]-9H-fluorene
  • 3-trifluoromethyl-4-fluoro phenyl boronic acid

Synthesis Reference(s)

Journal of the American Chemical Society, 69, p. 2022, 1947 DOI: 10.1021/ja01200a060

General Description

5-Bromo-2-fluorobenzotrifluoride is commonly used in the preparation poly(arylene ether)s (PAEs).

Properties of 2-Fluoro-5-bromobenzotrifluoride

Melting point: 203 °C(Solv: hexane (110-54-3))
Boiling point: 79-80 °C/50 mmHg (lit.)
Density  1.72 g/mL at 25 °C (lit.)
refractive index  n20/D 1.462(lit.)
Flash point: >230 °F
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
form  Liquid
color  Clear colorless to pale yellow
Specific Gravity 1.720
Water Solubility  Soluble in water 700 g/L (20°C)
BRN  2643550
CAS DataBase Reference 393-37-3(CAS DataBase Reference)

Safety information for 2-Fluoro-5-bromobenzotrifluoride

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405:Store locked up.

Computed Descriptors for 2-Fluoro-5-bromobenzotrifluoride

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