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HomeProduct name list2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl

2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl

Synonym(s):SPhos;S Phos;2-Dicyclohexylphosphino-2′,6′-dimethoxybiphenyl;2-Dicyclohexylphosphino-2′,6′-dimethoxybiphenyl impregnated tablets;ChemDose, S-Phos tablets

  • CAS NO.:657408-07-6
  • Empirical Formula: C26H35O2P
  • Molecular Weight: 410.53
  • MDL number: MFCD05861611
  • EINECS: 613-838-2
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-08-21 22:41:43
2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl Structural

What is 2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl?

Chemical properties

White solid

The Uses of 2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl

suzuki reaction

The Uses of 2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl

S-Phos is a catalyst that is used in the preparation of thiadiazoles as DGAT1 inhibitors with potential in metabolic diseases treatment.

General Description

SPhos [2-Dicyclohexylphosphino-2′, 6′-dimethoxybiphenyl] is an air-stable, electron-rich biaryl phosphine ligand developed by the Buchwald group to enhance the reactivity of palladium catalysis during cross-coupling reactions.

Properties of 2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl

Melting point: 164-166°C
Boiling point: 513.3±40.0 °C(Predicted)
storage temp.  Inert atmosphere,Room Temperature
solubility  soluble in Chloroform
appearance Colorless solid
form  crystal
color  white
Sensitive  Air Sensitive

Safety information for 2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl

Signal word Warning
Pictogram(s)
ghs
Health Hazard
GHS08
GHS Hazard Statements H351:Carcinogenicity
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.

Computed Descriptors for 2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl

InChIKey VNFWTIYUKDMAOP-UHFFFAOYSA-N

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