2'-DEOXY-N6-METHYLADENOSINE 3',5'-BISPHOSPHATE TETRAAMMONIUM SALT
Synonym(s):2′-Deoxy-N6-methyl adenosine 3′,5′-diphosphate diammonium salt
- CAS NO.：101204-49-3
- Empirical Formula: C11H17N5O9P2
- Molecular Weight: 425.23
- MDL number: MFCD08544553
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 16:48:35
What is 2'-DEOXY-N6-METHYLADENOSINE 3',5'-BISPHOSPHATE TETRAAMMONIUM SALT?
The Uses of 2'-DEOXY-N6-METHYLADENOSINE 3',5'-BISPHOSPHATE TETRAAMMONIUM SALT
MRS 2179 ammonium salt hydrate has been used as a P2Y1 receptor antagonist in porcine coronary small arteries, endothelial cells, and hippocampal astrocytes.
What are the applications of Application
MRS 2179 ammonium salt is a competitive P2Y12 (P2Y1 puinoreceptor) antagonist
Biological Activity
A competitive antagonist at P2Y 1 receptors (K B = 100 nM). Selective over P2X 1 (IC 50 = 1.15 μ M), P2X 3 (IC 50 = 12.9 μ M), P2X 2 , P2X 4 , P2Y 2 , P2Y 4 and P2Y 6 receptors.
Biochem/physiol Actions
MRS 2179 resists localized venous thrombosis and is useful in treating thrombotic syndromes due to its platelet aggregation inhibition functionality.
Properties of 2'-DEOXY-N6-METHYLADENOSINE 3',5'-BISPHOSPHATE TETRAAMMONIUM SALT
| Boiling point: | 821.6±75.0 °C(Predicted) |
| Density | 2.15±0.1 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | DMSO: 1.1 mg/mL |
| pka | 1.83±0.10(Predicted) |
Safety information for 2'-DEOXY-N6-METHYLADENOSINE 3',5'-BISPHOSPHATE TETRAAMMONIUM SALT
Computed Descriptors for 2'-DEOXY-N6-METHYLADENOSINE 3',5'-BISPHOSPHATE TETRAAMMONIUM SALT
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