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HomeProduct name list2'-DEOXY-N6-METHYLADENOSINE 3',5'-BISPHOSPHATE TETRAAMMONIUM SALT

2'-DEOXY-N6-METHYLADENOSINE 3',5'-BISPHOSPHATE TETRAAMMONIUM SALT

Synonym(s):2′-Deoxy-N6-methyl adenosine 3′,5′-diphosphate diammonium salt

2'-DEOXY-N6-METHYLADENOSINE 3',5'-BISPHOSPHATE TETRAAMMONIUM SALT Structural

What is 2'-DEOXY-N6-METHYLADENOSINE 3',5'-BISPHOSPHATE TETRAAMMONIUM SALT?

The Uses of 2'-DEOXY-N6-METHYLADENOSINE 3',5'-BISPHOSPHATE TETRAAMMONIUM SALT

MRS 2179 ammonium salt hydrate has been used as a P2Y1 receptor antagonist in porcine coronary small arteries, endothelial cells, and hippocampal astrocytes.

What are the applications of Application

MRS 2179 ammonium salt is a competitive P2Y12 (P2Y1 puinoreceptor) antagonist

Biological Activity

A competitive antagonist at P2Y 1 receptors (K B = 100 nM). Selective over P2X 1 (IC 50 = 1.15 μ M), P2X 3 (IC 50 = 12.9 μ M), P2X 2 , P2X 4 , P2Y 2 , P2Y 4 and P2Y 6 receptors.

Biochem/physiol Actions

MRS 2179 resists localized venous thrombosis and is useful in treating thrombotic syndromes due to its platelet aggregation inhibition functionality.

Properties of 2'-DEOXY-N6-METHYLADENOSINE 3',5'-BISPHOSPHATE TETRAAMMONIUM SALT

Boiling point: 821.6±75.0 °C(Predicted)
Density  2.15±0.1 g/cm3(Predicted)
storage temp.  −20°C
solubility  DMSO: 1.1 mg/mL
pka 1.83±0.10(Predicted)

Safety information for 2'-DEOXY-N6-METHYLADENOSINE 3',5'-BISPHOSPHATE TETRAAMMONIUM SALT

Computed Descriptors for 2'-DEOXY-N6-METHYLADENOSINE 3',5'-BISPHOSPHATE TETRAAMMONIUM SALT

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