2-CHLOROMETHYL-3-TRIMETHYLSILYL-1-PROPENE
Synonym(s):2-(Chloromethyl)-3-trimethylsilyl-1-propene;2-(Trimethylsilylmethyl)allyl chloride
- CAS NO.：18388-03-9
- Empirical Formula: C7H15ClSi
- Molecular Weight: 162.73
- MDL number: MFCD00013253
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-15 10:44:01
What is 2-CHLOROMETHYL-3-TRIMETHYLSILYL-1-PROPENE?
The Uses of 2-CHLOROMETHYL-3-TRIMETHYLSILYL-1-PROPENE
2-??(Chloromethyl)??allyl-??trimethylsilane is one of the reagents to synthesize Leucasandrolide A Macrolide (I) via Mukaiyama aldol coupling.2-??(Chloromethyl)??allyl-??trimethylsilane was used in catalytic Sakurai reaction of a,??b-??enones.
Properties of 2-CHLOROMETHYL-3-TRIMETHYLSILYL-1-PROPENE
| Boiling point: | 162-163 °C/768 mmHg (lit.) |
| Density | 0.899 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | 110 °F |
| storage temp. | 2-8°C |
| solubility | Chloroform, Methanol (Slightly) |
| form | Oil |
| color | Clear Colourless |
| Specific Gravity | 0.899 |
| Hydrolytic Sensitivity | 4: no reaction with water under neutral conditions |
| BRN | 1747038 |
| Stability: | Moisture Sensitive |
Safety information for 2-CHLOROMETHYL-3-TRIMETHYLSILYL-1-PROPENE
| Signal word | Warning |
| Pictogram(s) |
 Flame Flammables GHS02  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H226:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P241:Use explosion-proof electrical/ventilating/lighting/…/equipment. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-CHLOROMETHYL-3-TRIMETHYLSILYL-1-PROPENE
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