2'-Chloroacetophenone

Synonym(s):1-(2-Chlorophenyl)ethanone;2′-Chloroacetophenone

CAS NO.：2142-68-9
Empirical Formula: C8H7ClO
Molecular Weight: 154.59
MDL number: MFCD00000560
EINECS: 218-397-6
SAFETY DATA SHEET (SDS)
Update Date: 2024-08-21 22:41:43

What is 2'-Chloroacetophenone?

Chemical properties

clear light yellow to amber liquid

The Uses of 2'-Chloroacetophenone

2''-Chloroacetophenone (cas# 2142-68-9) is a compound useful in organic synthesis.

The Uses of 2'-Chloroacetophenone

2′-Chloroacetophenone was employed as model substrate to investigate the enzymatic performance of Aspergillus terreus and Rhizopus oryzae in enantioselective bioreductions using glycerol as a co-solvent.

General Description

2′-Chloroacetophenone undergoes stereoselective reduction to (R)-2′-chloro-1-phenyl-ethanol by Saccharomyces cerevisiae B5. It is commonly used as lacrimator.

Properties of 2'-Chloroacetophenone

Melting point:	52-56C
Boiling point:	227-230 °C
Density	1.190 g/mL at 20 °C
refractive index	n20/D 1.544
Flash point:	192 °F
storage temp.	Store below +30°C.
solubility	Chloroform, DMSO (Slightly), Methanol (Slightly)
form	Liquid
color	Clear light yellow to amber
Specific Gravity	1.19
Sensitive	Lachrymatory
BRN	1858916
CAS DataBase Reference	2142-68-9(CAS DataBase Reference)
NIST Chemistry Reference	Ethanone, 1-(2-chlorophenyl)-(2142-68-9)
EPA Substance Registry System	Ethanone, 1-(2-chlorophenyl)- (2142-68-9)

Safety information for 2'-Chloroacetophenone

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.