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HomeProduct name list2-Chloro-5-iodopyridine

2-Chloro-5-iodopyridine

  • CAS NO.:69045-79-0
  • Empirical Formula: C5H3ClIN
  • Molecular Weight: 239.44
  • MDL number: MFCD01863635
  • EINECS: 627-359-1
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-01-01 23:31:51
2-Chloro-5-iodopyridine Structural

What is 2-Chloro-5-iodopyridine?

Chemical properties

off-white to yellow-beige crystalline powder or

The Uses of 2-Chloro-5-iodopyridine

2-Chloro-5-iodopyridine may be used as a reagent in the multi-step synthesis of (±)-epibatidine.
It may be used in the synthesis of:

  • 2-Chloro-5-phenylpyridine via Suzuki coupling reaction with phenylboronic acid dimethyl ester.
  • Exo-5- and exo-6- (6′-chloro-3′-pyridyl)-2-azabicyclo[2.2.1]heptanes via Heck coupling reaction with N-protected 2-azabicyclo[2.2.1]hept-5-enes.
  • Substituted diaryliodonium salts.
  • 3-Exo-5′-(2′-Chloropyridinyl)-8-(ethoxycarbonyl)-8-azabicyclo[3.2.1]octane.

General Description

2-Chloro-5-iodopyridine is a halo-substituted pyridine.

Properties of 2-Chloro-5-iodopyridine

Melting point: 95-98 °C (lit.)
Boiling point: 253.2±20.0 °C(Predicted)
Density  2.052±0.06 g/cm3(Predicted)
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
form  Crystalline Powder or Flakes
pka -2.00±0.10(Predicted)
color  Off-white to yellow-beige
Water Solubility  insoluble
Sensitive  Light Sensitive
BRN  108889
CAS DataBase Reference 69045-79-0(CAS DataBase Reference)

Safety information for 2-Chloro-5-iodopyridine

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 2-Chloro-5-iodopyridine

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