2-Chloro-5-iodopyridine
- CAS NO.:69045-79-0
- Empirical Formula: C5H3ClIN
- Molecular Weight: 239.44
- MDL number: MFCD01863635
- EINECS: 627-359-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-01-01 23:31:51
What is 2-Chloro-5-iodopyridine?
Chemical properties
off-white to yellow-beige crystalline powder or
The Uses of 2-Chloro-5-iodopyridine
2-Chloro-5-iodopyridine may be used as a reagent in the multi-step synthesis of (±)-epibatidine.
It may be used in the synthesis of:
- 2-Chloro-5-phenylpyridine via Suzuki coupling reaction with phenylboronic acid dimethyl ester.
- Exo-5- and exo-6- (6′-chloro-3′-pyridyl)-2-azabicyclo[2.2.1]heptanes via Heck coupling reaction with N-protected 2-azabicyclo[2.2.1]hept-5-enes.
- Substituted diaryliodonium salts.
- 3-Exo-5′-(2′-Chloropyridinyl)-8-(ethoxycarbonyl)-8-azabicyclo[3.2.1]octane.
General Description
2-Chloro-5-iodopyridine is a halo-substituted pyridine.
Properties of 2-Chloro-5-iodopyridine
Melting point: | 95-98 °C (lit.) |
Boiling point: | 253.2±20.0 °C(Predicted) |
Density | 2.052±0.06 g/cm3(Predicted) |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
form | Crystalline Powder or Flakes |
pka | -2.00±0.10(Predicted) |
color | Off-white to yellow-beige |
Water Solubility | insoluble |
Sensitive | Light Sensitive |
BRN | 108889 |
CAS DataBase Reference | 69045-79-0(CAS DataBase Reference) |
Safety information for 2-Chloro-5-iodopyridine
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-Chloro-5-iodopyridine
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