2-Chloro-3,5-dinitrobenzotrifluoride

CAS NO.：392-95-0
Empirical Formula: C7H2ClF3N2O4
Molecular Weight: 270.55
MDL number: MFCD00007076
EINECS: 206-883-0
SAFETY DATA SHEET (SDS)
Update Date: 2024-12-18 14:15:30

What is 2-Chloro-3,5-dinitrobenzotrifluoride?

Description

2-Chloro-3, 5-dinitrobenzotrifluoride is a derivative of dinitrobenzotrifluoride. It is used as an important raw material and intermediate in organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuffs. It can also be used to increase mutagenic activity in the glutathione transferase mutant (C36). It can also be used in Ultrahigh-performance liquid chromatography tandem mass spectrometry (UPLC-MS) for determination of 20 free amino acids.

Chemical properties

white to light yellow crystal powder

The Uses of 2-Chloro-3,5-dinitrobenzotrifluoride

A benzene derivative that increases mutagenic activity in the glutathione transferase mutant (C36).

The Uses of 2-Chloro-3,5-dinitrobenzotrifluoride

It is used to increase mutagenic activity in the glutathione transferase mutant (C36).

Hazard

Low toxicity by inhalation. A severe skin and eye irritant.

References

https://www.alfa.com/en/catalog/A10446/
http://www.fishersci.ca/shop/products/2-chloro-3-5-dinitrobenzotrifluoride-98/aaa1761706
Lin, Qin Bao, et al. "Use of 4-chloro-3, 5-dinitrobenzotrifluoride (CNBF) Derivatization and Ultrahigh-performance Liquid Chromatography Tandem Mass Spectrometry for the Determination of 20 Free Amino Acids in Chinese Jujube Date." Food Analytical Methods 7.3(2014):571-579.

Properties of 2-Chloro-3,5-dinitrobenzotrifluoride

Melting point:	62-64 °C(lit.)
Boiling point:	250C
Density	1.706±0.06 g/cm3(Predicted)
solubility	Chloroform (Slightly), Methanol (Slightly)
Water Solubility	Insoluble in water. Soluble in Chloroform, Methanol.
BRN	2061156
CAS DataBase Reference	392-95-0(CAS DataBase Reference)
EPA Substance Registry System	Benzene, 2-chloro-1,5-dinitro-3-(trifluoromethyl)- (392-95-0)

Safety information for 2-Chloro-3,5-dinitrobenzotrifluoride

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Skull and Crossbones Acute Toxicity GHS06 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H312:Acute toxicity,dermal H314:Skin corrosion/irritation H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation H331:Acute toxicity,inhalation H332:Acute toxicity,inhalation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.