(2-BROMOETHOXY)-TERT-BUTYLDIMETHYLSILANE
- CAS NO.：86864-60-0
- Empirical Formula: C8H19BrOSi
- Molecular Weight: 239.23
- MDL number: MFCD00209550
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-08 17:06:38
What is (2-BROMOETHOXY)-TERT-BUTYLDIMETHYLSILANE?
Chemical properties
colorless liquid
The Uses of (2-BROMOETHOXY)-TERT-BUTYLDIMETHYLSILANE
(2-Bromoethoxy)-tert-butyldimethylsilane can be used in N-alkylation with 5-piperazin-1-yl-1H-indole to synthesize 5-(4-(2-((tert-butyldimethylsilyl)oxy)ethyl)piperazin-1-yl)-1H-indole.
The Uses of (2-BROMOETHOXY)-TERT-BUTYLDIMETHYLSILANE
(2-Bromoethoxy)-tert-butyldimethylsilane was used in the synthesis of 4-(3-hydroxypropyl)-4′-methyl-2,2′-bipyridine.
It may be used as a reagent for the selective N-alkylation of 5-piperazin-1-yl-1H-indole and (1H-indol-2-yl)-piperazin-1-yl-methanone and also in the synthesis of 2-[3-[(3,4,5-trimethoxyphenyl)thio]-1H-indol-5-yloxy]ethanol.
What are the applications of Application
(2-Bromoethoxy)-tert-butyldimethylsilane is a reagent for N-protection with the TBSO-ethyl group
General Description
(2-Bromoethoxy)-tert-butyldimethylsilane is a silane derivative.
Properties of (2-BROMOETHOXY)-TERT-BUTYLDIMETHYLSILANE
| Boiling point: | 70-75 °C2.5 mm Hg(lit.) |
| Density | 1.115 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | 163 °F |
| storage temp. | 2-8°C |
| form | Liquid |
| Specific Gravity | 1.115 |
| color | White to pale yellow |
| Hydrolytic Sensitivity | 7: reacts slowly with moisture/water |
Safety information for (2-BROMOETHOXY)-TERT-BUTYLDIMETHYLSILANE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for (2-BROMOETHOXY)-TERT-BUTYLDIMETHYLSILANE
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product: 2-Bromoethoxy-t-butyldimethylsilane 98%
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