(2-BROMOETHOXY)-TERT-BUTYLDIMETHYLSILANE

CAS NO.：86864-60-0
Empirical Formula: C8H19BrOSi
Molecular Weight: 239.23
MDL number: MFCD00209550
SAFETY DATA SHEET (SDS)
Update Date: 2023-06-08 17:06:38

What is (2-BROMOETHOXY)-TERT-BUTYLDIMETHYLSILANE?

Chemical properties

colorless liquid

The Uses of (2-BROMOETHOXY)-TERT-BUTYLDIMETHYLSILANE

(2-Bromoethoxy)-tert-butyldimethylsilane can be used in N-alkylation with 5-piperazin-1-yl-1H-indole to synthesize 5-(4-(2-((tert-butyldimethylsilyl)oxy)ethyl)piperazin-1-yl)-1H-indole.

The Uses of (2-BROMOETHOXY)-TERT-BUTYLDIMETHYLSILANE

(2-Bromoethoxy)-tert-butyldimethylsilane was used in the synthesis of 4-(3-hydroxypropyl)-4′-methyl-2,2′-bipyridine.
It may be used as a reagent for the selective N-alkylation of 5-piperazin-1-yl-1H-indole and (1H-indol-2-yl)-piperazin-1-yl-methanone and also in the synthesis of 2-[3-[(3,4,5-trimethoxyphenyl)thio]-1H-indol-5-yloxy]ethanol.

What are the applications of Application

(2-Bromoethoxy)-tert-butyldimethylsilane is a reagent for N-protection with the TBSO-ethyl group

General Description

(2-Bromoethoxy)-tert-butyldimethylsilane is a silane derivative.

Properties of (2-BROMOETHOXY)-TERT-BUTYLDIMETHYLSILANE

Boiling point:	70-75 °C2.5 mm Hg(lit.)
Density	1.115 g/mL at 25 °C(lit.)
refractive index	n20/D 1.444(lit.)
Flash point:	163 °F
storage temp.	2-8°C
form	Liquid
Specific Gravity	1.115
color	White to pale yellow
Hydrolytic Sensitivity	7: reacts slowly with moisture/water

Safety information for (2-BROMOETHOXY)-TERT-BUTYLDIMETHYLSILANE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.