Phenacyl Bromide

Synonym(s):1-Acetyl-2-bromobenzene

CAS NO.：2142-69-0
Empirical Formula: C8H7BrO
Molecular Weight: 199.04
MDL number: MFCD00000067
EINECS: 218-398-1
SAFETY DATA SHEET (SDS)
Update Date: 2025-02-19 17:26:24

What is Phenacyl Bromide?

Chemical properties

Clear pale yellow to orange liquid

The Uses of Phenacyl Bromide

2-bromoacetophenone is employed in the selective derivatization of cytosine moieties for the determination of global DNA methylation by reversed phase high performance liquid chromatography with spectrofluorimetric detection.

The Uses of Phenacyl Bromide

2′-Bromoacetophenone (2-Bromoacetophenone) was used in the synthesis of novel series of non-condensed 5,5-bicycles.

General Description

2′-Bromoacetophenone (2-Bromoacetophenone) undergoes enantioselective addition reaction with phenylacetylene catalyzed by chiral camphorsulfonamide. It reacts with aliphatic primary amines in the presence of palladium catalyst to afford 3-methyleneisoindolin-1-ones.

Properties of Phenacyl Bromide

Melting point:	°C
Boiling point:	116-117 °C (12 mmHg)
Density	1.476 g/mL at 25 °C(lit.)
refractive index	n20/D 1.568(lit.)
Flash point:	>230 °F
storage temp.	Sealed in dry,Room Temperature
form	Liquid
color	Clear pale yellow to orange
Specific Gravity	1.476
Water Solubility	PRACTICALLY INSOLUBLE
BRN	1931534
CAS DataBase Reference	2142-69-0(CAS DataBase Reference)
NIST Chemistry Reference	Ethanone, 1-(2-bromophenyl)-(2142-69-0)

Safety information for Phenacyl Bromide

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.