2'-Bromoacetophenone
Synonym(s):1-Acetyl-2-bromobenzene
- CAS NO.:2142-69-0
- Empirical Formula: C8H7BrO
- Molecular Weight: 199.04
- MDL number: MFCD00000067
- EINECS: 218-398-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-12-24 16:54:11
What is 2'-Bromoacetophenone?
Chemical properties
Clear pale yellow to orange liquid
The Uses of 2'-Bromoacetophenone
2-bromoacetophenone is employed in the selective derivatization of cytosine moieties for the determination of global DNA methylation by reversed phase high performance liquid chromatography with spectrofluorimetric detection.
The Uses of 2'-Bromoacetophenone
2′-Bromoacetophenone (2-Bromoacetophenone) was used in the synthesis of novel series of non-condensed 5,5-bicycles.
General Description
2′-Bromoacetophenone (2-Bromoacetophenone) undergoes enantioselective addition reaction with phenylacetylene catalyzed by chiral camphorsulfonamide. It reacts with aliphatic primary amines in the presence of palladium catalyst to afford 3-methyleneisoindolin-1-ones.
Properties of 2'-Bromoacetophenone
Melting point: | °C |
Boiling point: | 116-117 °C (12 mmHg) |
Density | 1.476 g/mL at 25 °C(lit.) |
refractive index | n |
Flash point: | >230 °F |
storage temp. | Sealed in dry,Room Temperature |
form | Liquid |
color | Clear pale yellow to orange |
Specific Gravity | 1.476 |
Water Solubility | PRACTICALLY INSOLUBLE |
BRN | 1931534 |
CAS DataBase Reference | 2142-69-0(CAS DataBase Reference) |
NIST Chemistry Reference | Ethanone, 1-(2-bromophenyl)-(2142-69-0) |
Safety information for 2'-Bromoacetophenone
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2'-Bromoacetophenone
InChIKey | PIMNFNXBTGPCIL-UHFFFAOYSA-N |
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product: 2142-69-0 2'-Bromoacetophenone 99%
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