2-Aminobenzenethiol
Synonym(s):2-Aminobenzenethiol;2-Aminophenyl mercaptan;2-Aminothiophenol;2-Mercaptoaniline
- CAS NO.:137-07-5
- Empirical Formula: C6H7NS
- Molecular Weight: 125.19
- MDL number: MFCD00007702
- EINECS: 205-277-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-15 10:43:44
What is 2-Aminobenzenethiol?
Chemical properties
clear yellow to amber liquid
The Uses of 2-Aminobenzenethiol
A multifunctional compound which shows antioxidant activity in a skin cell model of UVA-induced stress.
The Uses of 2-Aminobenzenethiol
2-Aminothiophenol was used in the synthesis of 1,5-benzothiazepines derivatives by reacting with 1,3-diphenylpropenone derivatives and using aluminosilicate solid catalysts. It was also used in the synthesis of benzothiazole2 and 3-(benzothiazol-2-yl)coumarin derivatives. The ternary complexes of copper (II) with salicylidene-2-aminothiophenol (L) and glycine, alanine, valine and histidene amino acids.
The Uses of 2-Aminobenzenethiol
2-Aminothiophenol was used in one-pot synthesis of stable phosphonium ylides. It was also used in the synthesis of 2-[(2-benzothiazolylmethyl)thio]-benzenamine. It was used to functionalize silver nano particles for biological pH sensing based on surface enhanced Raman scattering.
Definition
ChEBI: 2-aminothiophenol is an aryl thiol that is thiophenol substituted at position 2 by an amino group. It has a role as a plant metabolite. It is a substituted aniline and an aryl thiol.
Synthesis Reference(s)
Journal of the American Chemical Society, 68, p. 1514, 1946 DOI: 10.1021/ja01212a038
General Description
2-Aminothiophenol couples with Amberlite XAD by means of an N=N spacer to prepare a new functionalized resin for on-line preconcentration of copper and cadmium.
Safety Profile
Poison by intraperitoneal route. Moderately toxic by ingestion. Moderately flammable. Can react with oxilzing materials. To fight fire, use water, foam, CO2, mist or spray, dry chemical
Properties of 2-Aminobenzenethiol
Melting point: | 23 °C |
Boiling point: | 70-72 °C0.2 mm Hg(lit.) |
Density | 1.17 g/mL at 25 °C(lit.) |
vapor pressure | 1 hPa (69 °C) |
refractive index | n |
Flash point: | 175 °F |
storage temp. | Store at <= 20°C. |
solubility | H2O: slightly soluble |
form | Liquid |
pka | pK1: <2(+1);pK2: 7.90(0) (25°C) |
color | Clear yellow to amber |
Water Solubility | INSOLUBLE |
Sensitive | Stench |
BRN | 606076 |
Stability: | Air Sensitive |
CAS DataBase Reference | 137-07-5(CAS DataBase Reference) |
NIST Chemistry Reference | Benzenethiol, 2-amino-(137-07-5) |
EPA Substance Registry System | Benzenethiol, 2-amino- (137-07-5) |
Safety information for 2-Aminobenzenethiol
Signal word | Danger |
Pictogram(s) |
Corrosion Corrosives GHS05 Exclamation Mark Irritant GHS07 Environment GHS09 |
GHS Hazard Statements |
H302:Acute toxicity,oral H314:Skin corrosion/irritation H400:Hazardous to the aquatic environment, acute hazard |
Precautionary Statement Codes |
P270:Do not eat, drink or smoke when using this product. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-Aminobenzenethiol
InChIKey | VRVRGVPWCUEOGV-UHFFFAOYSA-N |
Abamectin manufacturer
ALTRAKEM PHARMA LIFE SCIENCES PRIVATE LIMITED
JSK Chemicals
Rivashaa Agrotech Biopharma Pvt. Ltd.
Khagga Life Sciences
ALS INDIA LIFE SCIENCES
Asmee Chemicals
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