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HomeProduct name list2-Aminobenzenethiol

2-Aminobenzenethiol

Synonym(s):2-Aminobenzenethiol;2-Aminophenyl mercaptan;2-Aminothiophenol;2-Mercaptoaniline

  • CAS NO.:137-07-5
  • Empirical Formula: C6H7NS
  • Molecular Weight: 125.19
  • MDL number: MFCD00007702
  • EINECS: 205-277-3
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2025-09-25 17:15:13
2-Aminobenzenethiol Structural

What is 2-Aminobenzenethiol?

Chemical properties

clear yellow to amber liquid

The Uses of 2-Aminobenzenethiol

A multifunctional compound which shows antioxidant activity in a skin cell model of UVA-induced stress.

The Uses of 2-Aminobenzenethiol

2-Aminothiophenol was used in the synthesis of 1,5-benzothiazepines derivatives by reacting with 1,3-diphenylpropenone derivatives and using aluminosilicate solid catalysts. It was also used in the synthesis of benzothiazole2 and 3-(benzothiazol-2-yl)coumarin derivatives. The ternary complexes of copper (II) with salicylidene-2-aminothiophenol (L) and glycine, alanine, valine and histidene amino acids.

The Uses of 2-Aminobenzenethiol

2-Aminothiophenol was used in one-pot synthesis of stable phosphonium ylides. It was also used in the synthesis of 2-[(2-benzothiazolylmethyl)thio]-benzenamine. It was used to functionalize silver nano particles for biological pH sensing based on surface enhanced Raman scattering.

Definition

ChEBI: 2-aminothiophenol is an aryl thiol that is thiophenol substituted at position 2 by an amino group. It has a role as a plant metabolite. It is a substituted aniline and an aryl thiol.

Synthesis Reference(s)

Journal of the American Chemical Society, 68, p. 1514, 1946 DOI: 10.1021/ja01212a038

General Description

2-Aminothiophenol couples with Amberlite XAD by means of an N=N spacer to prepare a new functionalized resin for on-line preconcentration of copper and cadmium.

Safety Profile

Poison by intraperitoneal route. Moderately toxic by ingestion. Moderately flammable. Can react with oxilzing materials. To fight fire, use water, foam, CO2, mist or spray, dry chemical

Properties of 2-Aminobenzenethiol

Melting point: 23 °C
Boiling point: 70-72 °C0.2 mm Hg(lit.)
Density  1.17 g/mL at 25 °C(lit.)
vapor pressure  1 hPa (69 °C)
refractive index  n20/D 1.642(lit.)
Flash point: 175 °F
storage temp.  Store at <= 20°C.
solubility  H2O: slightly soluble
form  Liquid
pka pK1: <2(+1);pK2: 7.90(0) (25°C)
color  Clear yellow to amber
Water Solubility  INSOLUBLE
Sensitive  Stench
BRN  606076
Stability: Air Sensitive
CAS DataBase Reference 137-07-5(CAS DataBase Reference)
NIST Chemistry Reference Benzenethiol, 2-amino-(137-07-5)
EPA Substance Registry System Benzenethiol, 2-amino- (137-07-5)

Safety information for 2-Aminobenzenethiol

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
ghs
Exclamation Mark
Irritant
GHS07
ghs
Environment
GHS09
GHS Hazard Statements H302:Acute toxicity,oral
H314:Skin corrosion/irritation
H400:Hazardous to the aquatic environment, acute hazard
Precautionary Statement Codes P270:Do not eat, drink or smoke when using this product.
P273:Avoid release to the environment.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 2-Aminobenzenethiol

InChIKey VRVRGVPWCUEOGV-UHFFFAOYSA-N

2-Aminobenzenethiol manufacturer

JSK Chemicals

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SAKEM LLP

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Anami Organics

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