(2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE
Synonym(s):(2-Amino-4,5-dimethyl-3-thienyl)-[3-(trifluoromethyl)phenyl]methanone
- CAS NO.：132861-87-1
- Empirical Formula: C14H12F3NOS
- Molecular Weight: 299.31
- MDL number: MFCD01321053
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-23 13:36:13
![(2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE Structural](https://img.chemicalbook.in/CAS/GIF/132861-87-1.gif)
What is (2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE?
The Uses of (2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE
PD 81,723 is an allosteric potentiator that increases the functional effects of adenosine and adenosine analogs.
What are the applications of Application
PD 81,723 is an allosteric potentiator that increases the functional effects of adenosine and adenosine analogs
Biological Activity
Allosteric potentiator at the adenosine A 1 receptor; acts via agonist-dependent and -independent mechanisms. Enhances agonist affinity for, and increased t 1/2 of dissociation from, the receptor. Also inhibits basal and forskolin-stimulated adenylyl cyclase (AC) activity in A 1 receptors expressed in CHO cells, possibly via direct potentiation of constitutive receptor activity or by direct inhibition of AC. Active in vivo .
storage
Store at RT
Properties of (2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE
| Melting point: | 100-104 °C(Solv: ligroine (8032-32-4)) |
| Boiling point: | 411.7±45.0 °C(Predicted) |
| Density | 1.328±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | DMSO: ~13 mg/mL |
| form | solid |
| pka | -1.36±0.13(Predicted) |
| color | yellow |
Safety information for (2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE
Computed Descriptors for (2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE
New Products
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