2-Amino-4-(trifluoromethyl)pyridine
- CAS NO.：106447-97-6
- Empirical Formula: C6H5F3N2
- Molecular Weight: 162.11
- MDL number: MFCD00077455
- EINECS: 634-596-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-11-16 16:15:21
What is 2-Amino-4-(trifluoromethyl)pyridine?
The Uses of 2-Amino-4-(trifluoromethyl)pyridine
2-Amino-4-trifluoromethylpyridine is a 2-amino-substituted nitrogen-containing six-membered heterocyclic compound, which is used as an important pharmaceutical intermediate.
Synthesis
2-Amino-4-(trifluoromethyl)pyridine can be synthesized by chemical reaction of 2-fluoro-4-trifluoromethyl-pyridine, acetamidine hydrochloride, NaOH, H2O and dimethyl sulfoxide under certain conditions.
Properties of 2-Amino-4-(trifluoromethyl)pyridine
| Melting point: | 70-74 °C |
| Boiling point: | 221.3±40.0 °C(Predicted) |
| Density | 1.368±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | Powder, Solid or Crystalline |
| pka | 4.55±0.11(Predicted) |
| color | White to pale brown |
| BRN | 7869677 |
| CAS DataBase Reference | 106447-97-6(CAS DataBase Reference) |
Safety information for 2-Amino-4-(trifluoromethyl)pyridine
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H300:Acute toxicity,oral H315:Skin corrosion/irritation H317:Sensitisation, Skin H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-Amino-4-(trifluoromethyl)pyridine
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