2-Amino-4-hydroxy-1H-pteridine
Synonym(s):2-Amino-4-hydroxypteridine;2-Amino-4-oxodihydropteridine
- CAS NO.：2236-60-4
- Empirical Formula: C6H5N5O
- Molecular Weight: 163.14
- MDL number: MFCD00010557
- EINECS: 218-799-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-04 17:34:36
What is 2-Amino-4-hydroxy-1H-pteridine?
Chemical properties
YELLOW-BEIGE CRYSTALLINE POWDER
The Uses of 2-Amino-4-hydroxy-1H-pteridine
Pterin is used in the biosynthesis and metabolism of tetrahydrobiopterin and molybdopterin.
Definition
ChEBI: 2-aminopteridin-4-ol is a 2-amino-4-hydroxypteridine. It is a tautomer of a 2-aminopteridin-4(3H)-one and a 2-aminopteridin-4(1H)-one.
Purification Methods
It is dissolved in hot 1% aqueous ammonia, filtered, and an equal volume of hot 1M aqueous formic acid is added. The solution is allowed to cool at 0-2o overnight. The solid is collected and washed with distilled water several times by centrifugation and dried in vacuo over P2O5 overnight, and then at 100o overnight (any ammonium formate in the sample evaporates off). [Beilstein 26 III/IV 3936.]
Properties of 2-Amino-4-hydroxy-1H-pteridine
| Melting point: | 300 °C |
| Boiling point: | 290.2°C (rough estimate) |
| Density | 1.4240 (rough estimate) |
| refractive index | 1.9000 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| pka | 2.27(at 20℃) |
| Water Solubility | 17.54mg/L(22.5 ºC) |
| BRN | 150294 |
| CAS DataBase Reference | 2236-60-4(CAS DataBase Reference) |
| NIST Chemistry Reference | 4(1H)-pteridinone, 2-amino-(2236-60-4) |
Safety information for 2-Amino-4-hydroxy-1H-pteridine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-Amino-4-hydroxy-1H-pteridine
| InChIKey | HNXQXTQTPAJEJL-UHFFFAOYSA-N |
New Products
(2S,4R)-4-amino-2-methyl-5-phenylpentanoic acid hydrochloride Tubulysin A Tubulysin E Diethyl Aluminium Cyanide (1.0 M in Toluene) Isoxazole, 3-[[[5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]methyl]thio]-4,5-dihydro-5,5-dimethyl- 3-FLUOROPYRROLIDINE HYDROCHLORIDE 4-CYANO-TETRAHYDROPYRAN-4-CARBOXYLIC ACID Methyl (R)-1-Boc-4,4-difluoropyrrolidine-2-carboxylate 2,2-Difluoropropylamine hydrochloride 2-(azetidin-3-ylidene)acetonitrile (hydrochloride) Imeglimin Hydrochloride IH (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile Calcium Sodium Phosphosilicate IH Fuel shell 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate Magnesium Trisilicate Lubiprostone Latanoprostene Bunod Flame Retardant Zinc Borate methyl 3-fluoro-4- thiomorpholino phenylcarbamate (R)-(3-(3-fluoro-4- thiomorpholinophenyl)-2- oxooxazolidin-4-yl) methyl methanesulfonate 1H-Imidazole-4-carbonitrile 7-Methoxyquinoline-4-carbonitrileRelated products of tetrahydrofuran
![(2S)-2-[[4-[Bis[(2-aMino-4-oxo-1,4-dihydropteridin-6-yl)Methyl]aMino]benzoyl]aMino]pentanedioic Acid](https://img.chemicalbook.in/CAS/20130318/GIF/1391068-26-0.gif)
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