2-Acetyl-5-bromothiophene

Synonym(s):5-Bromo-2-thienyl methyl ketone

CAS NO.：5370-25-2
Empirical Formula: C6H5BrOS
Molecular Weight: 205.07
MDL number: MFCD00014528
EINECS: 226-363-7
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is 2-Acetyl-5-bromothiophene?

Chemical properties

white to light yellow crystal powder

The Uses of 2-Acetyl-5-bromothiophene

2-Acetyl-5-bromothiophene was used as a starting reagent in the synthesis of bithiophene bis-imidazo[1,2-a]pyridine derivatives. It was also used in the preparation of phosphorus-containing fused bicyclic 5,6-membered compounds.

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 18, p. 1345, 1981 DOI: 10.1002/jhet.5570180714
Synthetic Communications, 11, p. 29, 1981 DOI: 10.1080/00397918108064279

Properties of 2-Acetyl-5-bromothiophene

Melting point:	94-96 °C (lit.)
Boiling point:	103 °C/4 mmHg (lit.)
Density	1.649 (estimate)
Flash point:	103°C/4mm
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
solubility	soluble in Methanol
form	Crystalline Flakes or Powder
color	Yellow
Sensitive	Light Sensitive
BRN	113949
CAS DataBase Reference	5370-25-2(CAS DataBase Reference)
NIST Chemistry Reference	2-Acetyl-5-bromothiophene(5370-25-2)

Safety information for 2-Acetyl-5-bromothiophene

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H312:Acute toxicity,dermal H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H332:Acute toxicity,inhalation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.