2-Acetyl-5-bromothiophene
Synonym(s):5-Bromo-2-thienyl methyl ketone
- CAS NO.：5370-25-2
- Empirical Formula: C6H5BrOS
- Molecular Weight: 205.07
- MDL number: MFCD00014528
- EINECS: 226-363-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is 2-Acetyl-5-bromothiophene?
Chemical properties
white to light yellow crystal powder
The Uses of 2-Acetyl-5-bromothiophene
2-Acetyl-5-bromothiophene was used as a starting reagent in the synthesis of bithiophene bis-imidazo[1,2-a]pyridine derivatives. It was also used in the preparation of phosphorus-containing fused bicyclic 5,6-membered compounds.
Synthesis Reference(s)
Journal of Heterocyclic Chemistry, 18, p. 1345, 1981 DOI: 10.1002/jhet.5570180714
Synthetic Communications, 11, p. 29, 1981 DOI: 10.1080/00397918108064279
Properties of 2-Acetyl-5-bromothiophene
| Melting point: | 94-96 °C (lit.) |
| Boiling point: | 103 °C/4 mmHg (lit.) |
| Density | 1.649 (estimate) |
| Flash point: | 103°C/4mm |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| solubility | soluble in Methanol |
| form | Crystalline Flakes or Powder |
| color | Yellow |
| Sensitive | Light Sensitive |
| BRN | 113949 |
| CAS DataBase Reference | 5370-25-2(CAS DataBase Reference) |
| NIST Chemistry Reference | 2-Acetyl-5-bromothiophene(5370-25-2) |
Safety information for 2-Acetyl-5-bromothiophene
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H312:Acute toxicity,dermal H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H332:Acute toxicity,inhalation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-Acetyl-5-bromothiophene
| InChIKey | IGBZCOWXSCWSHO-UHFFFAOYSA-N |
2-Acetyl-5-bromothiophene manufacturer
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