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HomeProduct name list2-(4-[(4-METHOXYBENZYL)OXY]PHENYL)ACETONITRILE

2-(4-[(4-METHOXYBENZYL)OXY]PHENYL)ACETONITRILE

2-(4-[(4-METHOXYBENZYL)OXY]PHENYL)ACETONITRILE Structural

What is 2-(4-[(4-METHOXYBENZYL)OXY]PHENYL)ACETONITRILE?

Description

O4I1 is an inducer of Oct3/4 expression and translation in diverse human cell lines (increases Oct3/4 mRNA in HEK293 cells by 2.5- and 4-fold at 10 and 20 μM, respectively). It also induces Oct3/4 expression and translation in terminally differentiated human fibroblasts. Through this action, O4I1 promotes the expression of pluripotency-associated genes in human neonatal foreskin fibroblasts.

The Uses of 2-(4-[(4-METHOXYBENZYL)OXY]PHENYL)ACETONITRILE

O4I1 is a potent Oct3/4 inducer. It promotes expression and stabilization of Oct3/4, and also enhanced its transcriptional activity in human somatic cells, making it useful in regenerative medicine.

Properties of 2-(4-[(4-METHOXYBENZYL)OXY]PHENYL)ACETONITRILE

Boiling point: 424.5±30.0 °C(Predicted)
Density  1.129±0.06 g/cm3(Predicted)
storage temp.  Sealed in dry,Room Temperature
solubility  DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2)(1:5): 0.16 mg/ml; Ethanol: slightly
form  A crystalline solid
color  Light yellow to yellow

Safety information for 2-(4-[(4-METHOXYBENZYL)OXY]PHENYL)ACETONITRILE

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P222:Do not allow contact with air.
P231:Handle under inert gas.
P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P422:Store contents under …
P403+P233:Store in a well-ventilated place. Keep container tightly closed.
P501:Dispose of contents/container to..…

Computed Descriptors for 2-(4-[(4-METHOXYBENZYL)OXY]PHENYL)ACETONITRILE

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